1148-49-8 Usage
General Description
4-HYDROXY-6-METHYL-2-PHENYLQUINOLINE is a chemical compound with the molecular formula C17H13NO. It is a quinoline derivative with a hydroxyl group and a methyl group attached to the 4th and 6th positions of the quinoline ring, respectively, along with a phenyl group attached to the 2nd position. This chemical has potential applications in the field of medicinal chemistry, particularly in the development of pharmaceutical drugs and other biologically active compounds. Its unique structure and functional groups make it a valuable building block for synthesizing novel molecules with potential therapeutic properties. Further research is needed to fully explore the potential uses and applications of 4-HYDROXY-6-METHYL-2-PHENYLQUINOLINE in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 1148-49-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,4 and 8 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1148-49:
(6*1)+(5*1)+(4*4)+(3*8)+(2*4)+(1*9)=68
68 % 10 = 8
So 1148-49-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H13NO/c1-11-7-8-14-13(9-11)16(18)10-15(17-14)12-5-3-2-4-6-12/h2-10H,1H3,(H,17,18)
1148-49-8Relevant articles and documents
Quinoline derivatives as antitubercular/antibacterial agents
Desai,Desai, Pratibha,Machhi, Dilip,Desai,Patel, Dinesh
, p. 871 - 873 (2007/10/03)
A number of quinoline derivatives of known antibacterial agents have been prepared and tested against the micro-organisms S. coli, S. paratyphi B, S. aureus and in particular against Mycobacterium tuberculosis H37-Rv. It has not been possibfe to establish correlation between antibacterial and antitubercular activities of these compounds. However, the antitubercular effect at MIC of 5 μg/mL against H37Rv shows that many modified compounds are more inhibitory than the parent agents such as 3-aminophenol, sulphamethoxazole, sulphaphenazole, sulphathiazole and monoacetyldapsone; among these the most effective are those with substituents such as 6-methyl, 6-chloro, 6-ethoxy-, or 8-methoxy functions in quinoline moiety.
