1148-49-8 Usage
Uses
Used in Pharmaceutical Industry:
4-HYDROXY-6-METHYL-2-PHENYLQUINOLINE is used as a key intermediate in the synthesis of various pharmaceutical drugs and biologically active compounds. Its unique structure and functional groups contribute to the development of novel molecules with potential therapeutic properties.
Used in Medicinal Chemistry Research:
4-HYDROXY-6-METHYL-2-PHENYLQUINOLINE serves as a valuable building block for researchers in medicinal chemistry to explore its potential uses and applications in the synthesis of new compounds with therapeutic effects. Further research is required to fully understand and harness its capabilities in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 1148-49-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,4 and 8 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1148-49:
(6*1)+(5*1)+(4*4)+(3*8)+(2*4)+(1*9)=68
68 % 10 = 8
So 1148-49-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H13NO/c1-11-7-8-14-13(9-11)16(18)10-15(17-14)12-5-3-2-4-6-12/h2-10H,1H3,(H,17,18)
1148-49-8Relevant academic research and scientific papers
Quinoline derivatives as antitubercular/antibacterial agents
Desai,Desai, Pratibha,Machhi, Dilip,Desai,Patel, Dinesh
, p. 871 - 873 (2007/10/03)
A number of quinoline derivatives of known antibacterial agents have been prepared and tested against the micro-organisms S. coli, S. paratyphi B, S. aureus and in particular against Mycobacterium tuberculosis H37-Rv. It has not been possibfe to establish correlation between antibacterial and antitubercular activities of these compounds. However, the antitubercular effect at MIC of 5 μg/mL against H37Rv shows that many modified compounds are more inhibitory than the parent agents such as 3-aminophenol, sulphamethoxazole, sulphaphenazole, sulphathiazole and monoacetyldapsone; among these the most effective are those with substituents such as 6-methyl, 6-chloro, 6-ethoxy-, or 8-methoxy functions in quinoline moiety.
