114840-33-4

Upstream product

• 528-48-3 3,7,3',4'-tetrahydroxyflavone 
• 108-24-7 acetic anhydride 
• 117-39-5 quercetol 
• 1064-06-8 3,5,7-triacetoxy-2-(3,4-diacetoxy-phenyl)-chromen-4-one 
• 7251-37-8 4-(3,7-diacetoxy-5-hydroxy-4-oxo-4H-chromen-2-yl)-1,2-phenylene diacetate 

Downstream Products

• 528-48-3 3,7,3',4'-tetrahydroxyflavone 

Relevant academic research and scientific papers

Synthesis of fisetin and 2′,4′,6′-trihydroxydihyrochalcone 4′-O-β-neohesperidoside based on site-selective deacetylation and deoxygenation

Fisetin and 2′,4′,6′-trihydroxydihyrochalcone 4′-O-β-neohesperidoside were synthesized from commercially available quercetin and naringin in five steps. The key steps are site-selective deacetylation and subsequent deoxygenation. The target molecules were obtained in 37% and 23% yields from the starting materials, respectively.

α-HYDROXYDIHYDROCHALCONES AND RELATED 1,3-DIARYLPROPAN-2-ONES FROM XANTHOCERCIS ZAMBESIACA

Key Word Index-Xanthocercis zambesiaca; Leguminosae; 7,8-dioxyisoflavonoids; α-hydroxydihydrochalcones; 1,3-diarylpropan-2-ones.Abstract-In addition to some previously described 7,8-dioxy-isoflavonoids and 2-benzylbenzofuran-3(2H)-ones the heartwood of Xanthocercis zambesiaca has been shown to contain 7,8,3'-trihydroxy-4'-methoxyisoflavone.These are accompained by the novel α,3,4,4'-tetrahydroxy-2'-methoxydihydrochalcone and its 3-deoxy analogue, the latter of which presumably served as biogenetic precursor for the unique 1-hydroxy-3-(4-hydroxyphenyl)-1-(4-hydroxy-2-methoxyphenyl) propan-2-one and its 1-deoxy analogue.Such possible biosynthetic relationship was demonstrated by the facile in vitro transformations of the appropriate α-hydroxydihydrochalcone into the different 1,3-diarylpropan-2-ones.