114840-33-4Relevant articles and documents
Synthesis of fisetin and 2′,4′,6′-trihydroxydihyrochalcone 4′-O-β-neohesperidoside based on site-selective deacetylation and deoxygenation
Tsunekawa, Ryuji,Hanaya, Kengo,Higashibayashi, Shuhei,Sugai, Takeshi
, p. 1316 - 1322 (2018)
Fisetin and 2′,4′,6′-trihydroxydihyrochalcone 4′-O-β-neohesperidoside were synthesized from commercially available quercetin and naringin in five steps. The key steps are site-selective deacetylation and subsequent deoxygenation. The target molecules were obtained in 37% and 23% yields from the starting materials, respectively.