114858-59-2Relevant academic research and scientific papers
Design, synthesis, and antitumor activity of novel acylate of 6-OH at 1- O-acetylbritannilactone
Liu, Shouxin,Feng, Jun,Liu, He,Li, Junzhang,Tian, Xia
, p. 200 - 205 (2015/04/14)
N-(α-Alkyloxime-3-phenylpropionyl) proline was designed and synthesized as an acylating agent to modify the 6-OH of 1-O-acetylbritannilactone. Eight intermediates and eight target compounds were obtained. The structures of sixteen novel compounds were characterized by 1HNMR, IR and HRMS. The activities against HL-60 and Bel-7402 cell lines were tested, the IC50 values of compound IVg were 2.7 μM and 4.3 μM, respectively.
ALKYLATION OF ALKYL NITROACETATES UNDER PTC CONDITIONS
Gogte, V. N.,Natu, A. A.,Pore, V. S.
, p. 1421 - 1430 (2007/10/02)
Alkyl nitroacetates were alkylated to give C-alkylated products in good yields under PTC conditions.
