114908-25-7

Upstream product

• 3425-46-5 potassium selenocyanate 
• 2114-00-3 2-bromo-1-phenyl-1-propanone 
• 7677-24-9 trimethylsilyl cyanide 
• 93-55-0 1-phenyl-propan-1-one 
• 27151-67-3 dicyanodiselenide 

Relevant academic research and scientific papers

3-Hydroxythiazole and 1-hydroxyimidazole as products of a mutual ring closure reaction: Extension to selenium derivatives

A thiazole derivative can be easily prepared, e.g., from an α-thiocyanatoketone and a nitrogen nucleophile. In this work, α-bromopropiophenone was chosen as a starting compound. Since the carbonyl group facilitates nucleophilic substitution, bromine can b

N -Selenocyanato-Dibenzenesulfonimide: A New Electrophilic Selenocyanation Reagent

A new electrophilic selenocyanation reagent N -seleno-cyanato-dibenzenesulfonimide was readily prepared in two steps from commercially available dibenzenesulfonimide for the first time. A variety of electrophilic selenocyanato reactions of nucleophiles have been achieved using it as selenocyanato source under mild and simple conditions. Numerous SeCN-containing compounds were obtained in moderate to excellent yields. Meanwhile, a Lewis acid mediated tandem selenocyanation/cyclization reaction of alkenes with phenols, which provided simple methods for the formation of various SeCN-containing chromanes and dihydrobenzofurans in moderate to good yields, has also been developed.

α-Selective C(sp3)-H Thio/Selenocyanation of Ketones with Elemental Chalcogen

A facile method is disclosed for the synthesis of α-thio/selenocyanato ketones through regioselective C-H thio/selenocyanation of ketones. The advantages include the use of easily available starting materials, high efficiency, simple operation, and easy scale-up. Control experiments provide evidence that the reaction proceeded via a radical way, while kinetic isotope effect experiments reveal that the cleavage of the C-H bond serves as the rate-limiting step.

Oxidative umpolung selenocyanation of ketones and arenes: An efficient protocol to the synthesis of selenocyanates

A practical method for the umpolung selenocyanation of aryl ketones, alkyl ketones, β-ketoesters and electron-rich arenes has been developed, affording various selenocyanates in moderate to excellent yields. This transformation proceeds by an oxidative um

A novel metal-free method for the selenocyanation of aromatic ketones to afford α-carbonyl selenocyanates

A new method has been developed for the selenocyanation of aromatic ketones. This reaction avoids the need to use pre-prepared α-halo ketones, providing rapid access to α-carbonyl selenocyanates. We also investigated the mechanism for this reaction and found that it proceeds via sequential radical iodination and nucleophilic substitution reactions.

Preparation and Cycloaddition Reactions of Selenoketones

Dienophilic selenoketones have been prepared by base-induced elimination of cyanide from selenocyanates containing electron-withdrawing or conjugating substituents.Cycloaddition reactions of selenoketones with dienes or dipolar reagents proceed efficientl