114996-64-4

Basic information

• Product Name: 3-methylidene-1-(phenylsulfonyl)indoline
• Synonyms: 3-methylidene-1-(phenylsulfonyl)indoline
• CAS NO: 114996-64-4
• Molecular Weight: 271.34
• Mol File: 114996-64-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-methylidene-1-(phenylsulfonyl)indoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methylidene-1-(phenylsulfonyl)indoline(114996-64-4)
• EPA Substance Registry System: 3-methylidene-1-(phenylsulfonyl)indoline(114996-64-4)

Safety Data

• Hazardous Substances Data: 114996-64-4(Hazardous Substances Data)

Upstream product

• 21226-31-3 N-(2-bromophenyl)-S-phenylsulfonamide 
• 114996-61-1 N-(2-Bromo-phenyl)-N-prop-2-ynyl-benzenesulfonamide 

Downstream Products

• 58550-84-8 N-(phenylsulphonyl)-3-methylindole 
• 114996-66-6 1-phenylsulfonylindoline-3-methanol 

Relevant articles and documents

A novel approach to 3-methylindoles by a heck/cyclization/isomerization process

Chemical Equation presented A novel synthesis of 3-methyllndoles from chlorotrlflates through a Heck reaction, carbamate/aryl chloride coupling, and Isomerlzatlon sequence Is presented. The three-step sequence Is highly efficient and general, enabling the

Consice Synthesis of CC-1065/Duocarmycin Pharmacophore Using the Intramolecular Heck Reaction

3-Methyleneindoline derivatives were synthesized by intramolecular Heck reaction of N-allyl-2-iodoaniline derivatives in the presence of Ag2CO3.This method was successfully applied to the synthesis of the CC-1065/duocarmycin pharmacophore.