115029-23-7

Usage

Chemical Properties

White to off-white powder

Synthesis Reference(s)

Tetrahedron Letters, 33, p. 7495, 1992 DOI: 10.1016/S0040-4039(00)60805-5

InChI:InChI=1/C8H4F4O2/c9-6-2-1-4(8(10,11)12)3-5(6)7(13)14/h1-3H,(H,13,14)/p-1

Upstream product

• 124-38-9 carbon dioxide 
• 402-44-8 4-Fluorobenzotrifluoride 
• 13061-96-6 dihydroxy-methyl-borane 
• 351003-21-9 1-bromo-2-(trifluoromethyl)-5-fluorobenzene 
• 146137-78-2 2-fluoro-5-trifluoromethylbenzaldehyde 

Downstream Products

• 556112-92-6 2-fluoro-5-trifluoromethylbenzoic acid methyl ester 
• 847956-31-4 tert-butyl 2-(2-fluoro-5-(trifluoromethyl)benzamido)acetate 
• 439151-22-1 [2-Isopropylamino-5-(trifluoromethyl)]benzoic acid 
• 439151-18-5 allyl [2-fluoro-5-(trifluoromethyl)] benzoate 
• 247568-34-9 2-fluoro-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide 
• 247570-08-7 N-(3-chloro-4-methoxybenzyl)-2-fluoro-5-(trifluoromethyl)benzamide 
• 164341-27-9 2-Fluoro-5-trifluoromethylbenzoylguanidine hydrochloride 
• 865471-20-1 2-morpholino-5-(trifluoromethyl)benzoic acid 
• 1140918-76-8 N-[(2Z)-5-tert-butyl-3-[(2R)-tetrahydrofuran-2-ylmethyl]-1,3-oxazol-2(3H)-ylidene]-2-fluoro-5-(trifluoromethyl)benzamide 
• 1231955-35-3 N-[(2Z)-3-butyl[1,3]thiazolo[4,5-c]pyridin-2(3H)-ylidene]-2-fluoro-5-(trifluoromethyl)benzamide 
• 1231955-18-2 N-[(2Z)-3-butyl[1,3]thiazolo[4,5-c]pyridin-2(3H)-ylidene]-2-{[(2S)-2-hydroxypropyl]oxy}-5-(trifluoromethyl)benzamide 
• 1311319-00-2 (2S)-1-[2-{[(2Z)-3-butyl[1,3]thiazolo[4,5-c]pyridin-2(3H)-ylidene]carbamoyl}-4-(trifluoromethyl)phenoxy]propan-2-yl acetate 

Relevant academic research and scientific papers

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Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

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