115050-49-2Relevant academic research and scientific papers
Substituted indole - 2 - formic acid (by machine translation)
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Paragraph 0060; 0061, (2017/10/28)
This invention relates to a substituted indole - 2 - carboxylic acid synthesis method, is to replace the phenyl hydrazine hydrochloride or arylhydrazines as raw materials, through with pyruvic acid ethyl ester cheng zong, Fischer indole synthesis by reaction of substituted indole - 2 - carboxylic acid ethyl ester, hydrolysis to obtain the substituted - 2 - carboxylic acid. Product purity is greater than 97%, the reaction yield is 64%. Synthesis method of the invention with non-harsh conditions, the operation is simple, and environmental friendliness, it has certain economic benefits. It is a kind of raw materials are easy, simple operation, three wastes, high yield of indole - 2 - carboxylic acid synthesis method. (by machine translation)
A simple and efficient synthesis of ethyl 1-Aryl-4-formyl-1H-pyrazole-3- carboxylates
Matiychuk, Vasyl S.,Potopnyk, Mykhaylo A.,Obushak, Mykola D.
, p. E43-E47 (2013/06/04)
A new simple and convenient method of synthesis of ethyl 1-aryl-4-formyl-1H-pyrazole-3-carboxylates from aromatic amines via diazonium salts has been developed. Hydrolysis and hydrazinolyization of these compounds has been investigated.
