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2-Chloro-5,6-dihydrocyclopenta[b]pyridin-7-one is a heterocyclic chemical compound with the molecular formula C8H8ClNO. It features a cyclopentene ring with a chlorine atom attached and a ketone functional group, which contributes to its potential biological activities and diverse applications in pharmaceutical and agrochemical industries.

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  • SAGECHEM/2-chloro-5,6-dihydrocyclopenta[b]pyridin-7-one/SAGECHEM/Manufacturer in China

    Cas No: 1150617-92-7

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  • 1150617-92-7 Structure
  • Basic information

    1. Product Name: 2-chloro-5,6-dihydrocyclopenta[b]pyridin-7-one
    2. Synonyms: 2-chloro-5,6-dihydrocyclopenta[b]pyridin-7-one;2-chloro-5H-cyclopenta[b]pyridin-7(6H)-one;2-chloro-5,6-dihydro-7H-cyclopenta[b]pyridin-7-one;2-chloro-5H,6H,7H-cyclopenta[b]pyridin-7-one
    3. CAS NO:1150617-92-7
    4. Molecular Formula: C8H6ClNO
    5. Molecular Weight: 167.59234
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1150617-92-7.mol
  • Chemical Properties

    1. Melting Point: 136-138 °C
    2. Boiling Point: 313.568 °C at 760 mmHg
    3. Flash Point: 143.441 °C
    4. Appearance: /
    5. Density: 1.394 g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 0.78±0.20(Predicted)
    10. CAS DataBase Reference: 2-chloro-5,6-dihydrocyclopenta[b]pyridin-7-one(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-chloro-5,6-dihydrocyclopenta[b]pyridin-7-one(1150617-92-7)
    12. EPA Substance Registry System: 2-chloro-5,6-dihydrocyclopenta[b]pyridin-7-one(1150617-92-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1150617-92-7(Hazardous Substances Data)

1150617-92-7 Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-5,6-dihydrocyclopenta[b]pyridin-7-one is used as a pharmaceutical intermediate for the development of drugs targeting neurological disorders. Its unique structure and pharmacological properties make it a promising candidate for the treatment of various neurological conditions.
Used in Agrochemical Industry:
2-Chloro-5,6-dihydrocyclopenta[b]pyridin-7-one is used as an active ingredient in agrochemicals for its antibacterial and antifungal properties. It effectively inhibits the growth of certain plant pathogens, thereby protecting crops and improving agricultural productivity.

Check Digit Verification of cas no

The CAS Registry Mumber 1150617-92-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,0,6,1 and 7 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1150617-92:
(9*1)+(8*1)+(7*5)+(6*0)+(5*6)+(4*1)+(3*7)+(2*9)+(1*2)=127
127 % 10 = 7
So 1150617-92-7 is a valid CAS Registry Number.

1150617-92-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-chloro-5,6-dihydrocyclopenta[b]pyridin-7-one

1.2 Other means of identification

Product number -
Other names ZLD0285

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1150617-92-7 SDS

1150617-92-7Relevant articles and documents

Constrained formation of 2-(1-(arylimino)ethyl)-7-arylimino-6,6-dimethylcyclopentapyridines and their cobalt(ii) chloride complexes: Synthesis, characterization and ethylene polymerization

Ba, Junjun,Du, Shizhen,Yue, Erlin,Hu, Xinquan,Flisak, Zygmunt,Sun, Wen-Hua

, p. 32720 - 32729 (2015)

A series of 2-(1-(arylimino)ethyl)-7-arylimino-6,6-dimethylcyclopentapyridine derivatives (L1-L5) was synthesized, and individually reacted with cobalt(ii) chloride to form the corresponding cobalt chloride complexes (C1-C4). These compounds were characte

METHODS OF MAKING WEE1 INHIBITOR COMPOUNDS

-

Paragraph 0088, (2021/12/31)

The invention relates to a method of producing a WEE1 inhibitor of formula (1A) useful in the treatment of pathological conditions characterized by excessive cell proliferation, such as cancer. In some embodiments, the invention relates to methods for producing intermediate compounds of formulas (3), (5) and (6) as defined in the description.

IRAK4 INHIBITING AGENTS

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Page/Page column 112, (2016/03/13)

Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.

AMINOPYRAZINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES

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Paragraph 0236, (2016/06/21)

Disclosed are compounds of Formula A and Formula A-1, or a salt thereof, and pharmaceutical formulations (pharmaceutical compositions) comprising those compounds, or a salt thereof; wherein "R1", "RA-1", "R2", "R3", and "Het" are defined herein above, which compounds are believed suitable for use in selectively antagonizing the A2a receptors, for example, those found in high density in the basal ganglia. Such compounds and pharmaceutical formulations are believed to be useful in treatment or management of neurodegenerative diseases, for example, Parkinson's disease, or movement disorders arising from use of certain medications used in the treatment or management of Parkinson's disease.

AMIDE COMPOUND

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Page/Page column 70-71, (2011/04/18)

The present invention aims to provide a prophylactic or therapeutic agent for schizophrenia and the like, containing the compound of the present invention having a GPR52 agonist activity. A compound represented by the following formula (I) or a salt there

N-(HETERO)ARYL-PYRROLIDINE DERIVATIVES OF PYRAZOL-4-YL-PYRROLO[2,3-d]PYRIMIDINES AND PYRROL-3-YL-PYRROLO[2,3-d]PYRIMIDINES AS JANUS KINASE INHIBITORS

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Page/Page column 115, (2010/12/29)

The present invention relates to N-(hetero)aryl-pyrrolidine derivatives of Formula I: which are JAK inhibitors, such as selective JAK1 inhibitors, useful in the treatment of JAK-associated diseases including, for example, inflammatory and autoimmune disorders, as well as cancer.

Design and synthesis of new chiral pyridine-phosphite ligands for the copper-catalyzed enantioselective conjugate addition of diethylzinc to acyclic enones

Xie, Yinjun,Huang, Hanmin,Mo, Weimin,Fan, Xiangqun,Shen, Zhiqiang,Shen, Zhenlu,Sun, Nan,Hu, Baoxiang,Hu, Xinquan

experimental part, p. 1425 - 1432 (2009/12/04)

A series of new chiral pyridine-phosphite ligands have been prepared from (R)-pyridyl alcohols and BINOL-derived chlorophosphite, and successfully employed in the copper-catalyzed enantioselective conjugate addition of diethylzinc to acyclic enones. Using the simple and inexpensive CuBr2 as a precursor, the enantioselective additions to various substituted acyclic enones afforded products in high yields and good enantioselectivities (up to 92% ee).

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