1150654-80-0 Usage
Uses
Used in Organic Synthesis:
Potassium 1-trifluoroboratomethylthiomorpholine serves as a crucial reagent in organic synthesis, where it is employed for its capacity to react with a diverse array of organic molecules. This property is essential for the production of complex organic compounds that are integral to various industries.
Used in Pharmaceutical Production:
In the pharmaceutical industry, Potassium 1-trifluoroboratomethylthiomorpholine is utilized as a key intermediate in the synthesis of various drugs. Its ability to participate in multiple types of chemical reactions aids in the creation of new medicinal compounds with specific therapeutic properties.
Used in Agrochemical Development:
Similarly, in agrochemicals, Potassium 1-trifluoroboratomethylthiomorpholine is applied to synthesize active ingredients for pesticides and other crop protection products. Its versatility in organic synthesis contributes to the development of effective and targeted agrochemicals.
Used in Materials Science:
Potassium 1-trifluoroboratomethylthiomorpholine is also studied for its potential applications in materials science. Its unique structure and reactivity may contribute to the advancement of new materials with specific properties for various applications.
Used in Catalysis:
Furthermore, Potassium 1-trifluoroboratomethylthiomorpholine has been explored for its potential use in catalysis, where it could enhance the efficiency of chemical reactions in industrial processes, thereby improving the overall yield and reducing the environmental impact of chemical production.
Check Digit Verification of cas no
The CAS Registry Mumber 1150654-80-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,0,6,5 and 4 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1150654-80:
(9*1)+(8*1)+(7*5)+(6*0)+(5*6)+(4*5)+(3*4)+(2*8)+(1*0)=130
130 % 10 = 0
So 1150654-80-0 is a valid CAS Registry Number.
1150654-80-0Relevant academic research and scientific papers
Synthesis of Arylethylamines via C(sp3)-C(sp3) Palladium-Catalyzed Cross-Coupling
Lippa, Rhys A.,Battersby, David J.,Murphy, John A.,Barrett, Tim N.
, p. 3583 - 3604 (2021/02/27)
Substituted arylethylamines represent a key structural motif in natural, pharmaceutical, and agrochemical compounds. Access to such scaffolds has been the subject of long-standing synthetic interest. Herein, we report the synthesis of such scaffolds via a palladium-catalyzed C(sp3)-C(sp3) coupling between (chloromethyl)aryls and air-/moisture-stable N,N-dialkylaminomethyltrifluoroborate salts. Rapid hit identification was achieved using microscale high-throughput experimentation and was followed by millimolar-scale reaction parameter optimization. A range of structurally and electronically varied arylethylamine products were obtained in moderate to excellent yields (27-96%, >60 examples). The reaction mechanism is proposed to proceed via formation of a trialkylbenzylammonium species prior to oxidative addition.
Cu(II)-Catalyzed ortho-Selective Aminomethylation of Phenols
Dai, Jin-Ling,Shao, Nan-Qi,Zhang, Jin,Jia, Run-Ping,Wang, Dong-Hui
supporting information, p. 12390 - 12393 (2017/09/23)
A Cu(II)-catalyzed ortho-selective functionalization of free phenols with trifluoroborates to afford Csp2-Csp3 coupling products under mild conditions has been developed. A variety of functional groups on the phenol and the potassium aminomethyltrifluoroborate substrates were found compatible, furnishing the corresponding products in moderate to excellent yields. A single-electron transfer radical coupling mechanism involving a six-membered transition state is proposed to rationalize the high levels of ortho-selectivity in the reaction. This protocol provides straightforward access to ortho-aminomethyl-substituted phenols, unnatural amino acids and other bioactive small molecules.
