115071-96-0Relevant academic research and scientific papers
Rapid three-component synthesis of pyrimidine and pyrimidinone derivatives in the presence of Bi(NO3)3·5H2O as a mild and highly efficient catalyst
Zahedifar, Moahboobeh,Sheibani, Hassan
, p. 105 - 111 (2015/01/30)
Bismuth(III) nitrate pentahydrate is found as a mild and highly efficient catalyst for the rapid synthesis of 4-amino-5-pyrimidine carbonitrile and pyrimidinone derivatives via three-component reaction of aldehydes, N-unsubstituted amidines, and malononit
Granulated copper oxide nanocatalyst: A mild and efficient reusable catalyst for the one-pot synthesis of 4-amino-5-pyrimidinecarbonitriles under aqueous conditions
Ahmadi, Seyed Javad,Sadjadi, Sodeh,Hosseinpour, Morteza
experimental part, p. 1163 - 1168 (2012/01/06)
An efficient method for the synthesis of 4-amino-5-pyrimidinecarbonitriles by the three-component reaction of malononitrile, aldehydes, and N-unsubstituted amidines under aqueous conditions using CuO microspheres as catalyst is reported. The catalyst exhibited remarkable reusable activity. Graphical abstract: [Figure not available: see fulltext.]
Three-component synthesis of pyrimidine and pyrimidinone derivatives in the presence of high-surface-area MgO, a highly effective heterogeneous base catalyst
Sheibani, Hassan,Seifi, Mohammad,Bazgir, Ayoob
experimental part, p. 1055 - 1064 (2009/09/08)
Magnesium oxide (MgO) effectively catalyzes the three-component reaction of aldehydes, amidine systems, and malononitrile or ethyl cyanoacetate to form 4-amino-5-pyrimidine carbonitrile and pyrimidinone derivatives, respectively. The salient features of t
One-step synthesis of aminopyrimidines from 5-oxo-4H-benzopyrans
Salfran, Esperanza,Suarez, Margarita,Verdecia, Yamila,Alvarez, Amaury,Ochoa, Estael,Martinez-Alvarez, Roberto,Seoaneb, Carlos,Martin, Nazario
, p. 509 - 516 (2007/10/03)
Novel 4-amino-6-aryl-2-phenylpyrimidine-5-carbonitriles have been prepared in one step procedure from the readily available 4-aryl-2-amino-3-cyano-5,6,7,8- tetrahydro-7,7-dimethyl-5-oxo-4H-benzopyrans. The mass spectroscopy study under EI conditions shows
REACTIONS WITH α-THIOCARBAMOYLCINNAMONITRILES: SYNTHESIS OF PYRAZOLOPYRIMIDINES
Hussain, Sohair Mohamed,El-Reedy, Ahmed Mohamed,El-Sharabasy, Salwa Ahmed
, p. 241 - 246 (2007/10/02)
Whereas each of α-thiocarbamoyl- and α-cyanomalononitrile derivatives 1a and 1d reacted whith benzamidine (2) hydrochloride to give only 4-amino-6-(4-chlorophenyl)-2-phenyl-5-pyrimidine-carbonitrile (5a), they react with 5-amino-3-phenylpyrazole(6) to yie
