68029-58-3

Upstream product

• 7357-70-2 Cyanothioacetamide 
• 2826-28-0 p-(N-dimethylamino benzylidene) malononitrile 
• 100-10-7 4-dimethylamino-benzaldehyde 

Downstream Products

• 97651-31-5 5-Cyano-4-(4-dimethylamino-phenyl)-2-methyl-6-thioxo-1,6-dihydro-pyridine-3-carboxylic acid ethyl ester 
• 1374881-57-8 2-amino-4-(4-(dimethylamino)phenyl)-5,8-dihydro-6-hydroxy-5,8-dioxo-7-undecyl-4H-chromene-3-carbothioamide 
• 252001-73-3 5-acetyl-3-amino-4-(4-dimethylamino-phenyl)-6-methyl-thieno[2,3-b]pyridine-2-carboxylic acid ethyl ester 
• 252001-71-1 5-acetyl-3-amino-4-(4-dimethylamino-phenyl)-6-methyl-thieno[2,3-b]pyridine-2-carboxylic acid amide 

Relevant academic research and scientific papers

Synthesis of 4-methylmorpholinium 6-amino-3,5-dicyano-4-(furan-2-yl)pyridine-2-thio(seleno)lates and 3-[aryl(hetaryl)]-2-cyanoprop-2-enethioamides by michael reaction

Michael reaction of dimethyl (furan-2-ylmethylidene)malonate with 2-cyanoethanethio(seleno)amides and 4-methylmorpholine afforded 4-methylmorpholinium 6-amino-3,5-dicyano-4-(furan-2-yl)pyridine-2-thio(seleno)lates via exchange of the CH acid components. Aryl(hetaryl)methylidenemalononitriles reacted with cyanoethanethioamide under analogous conditions to give 3-aryl(hetaryl)-2-cyanoprop-2-enethioamides which were converted into 3-aryl(hetaryl)-2-(1,3-thiazol-2-yl)prop-2-enenitriles according to Hantzsch.

Zinc chloride-catalyzed one-pot, three-component synthesis of 5,8-dihydro-5,8-dioxo-4H-chromene derivatives

An efficient zinc chloride-catalyzed one-pot synthesis of 5,8-dihydro-5,8-dioxo-4H-chromene derivatives have been achieved by the reaction of 2,5-dihydroxy-6-undecyl-1,4-bezoquinone, cyanothioacetamide, and aromaticaldehyde, in EtOH at room temperature. The structures of the products were characterized by IR, 1H-NMR, mass spectra, and elemental analyses. Copyright

Condensation of α-cyanothioacetamide with aldehydes catalyzed by Envirocat EPZG

Condensation of α-cyanothioacetamide with aldehydes has been carried out in excellent yield under mild conditions by using Envirocat EPZG as a heterogenous reusable catalyst.