115104-27-3

Upstream product

• 124948-74-9 3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][(trimethylsilyl)oxy]methyl]thio]-N,N-dimethylpropanamide 
• 497-19-8 sodium carbonate 
• 115104-48-8 (R)-Methoxy-phenyl-thioacetic acid S-[[3-(tert-butyl-diphenyl-silanyloxymethyl)-phenyl]-(2-dimethylcarbamoyl-ethylsulfanyl)-methyl] ester 
• 115104-47-7 3-[[3-(tert-Butyl-diphenyl-silanyloxymethyl)-phenyl]-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-propionic acid methyl ester 
• 115104-50-2 3-[(2-Dimethylcarbamoyl-ethylsulfanyl)-(3-hydroxymethyl-phenyl)-methylsulfanyl]-propionic acid methyl ester 
• 110130-71-7 3-(((tert-butyldiphenylsilyl)oxy)methyl)benzaldehyde 
• 115104-25-1 2-(Bromomethyl)-7-chloroquinoline 
• 52010-98-7 3-(hydroxymethyl)benzaldehyde 
• 626-19-7 Isophthalaldehyde 
• 4965-33-7 2-methyl-7-chloroquinoline 
• 115125-09-2 ((7-chloroquinolin-2-yl)methyl)triphenylphosphonium bromide 
• 115104-51-3 3-[(2-Dimethylcarbamoyl-ethylsulfanyl)-(3-formyl-phenyl)-methylsulfanyl]-propionic acid methyl ester 
• 115104-48-8 (R)-Methoxy-phenyl-thioacetic acid S-[[3-(tert-butyl-diphenyl-silanyloxymethyl)-phenyl]-(2-dimethylcarbamoyl-ethylsulfanyl)-methyl] ester 
• 115104-47-7 3-[[3-(tert-Butyl-diphenyl-silanyloxymethyl)-phenyl]-(2-dimethylcarbamoyl-ethylsulfanyl)-methylsulfanyl]-propionic acid methyl ester 

Downstream Products

• 115104-28-4 (+)-L-660,711 
• 115104-28-4 (-)-L-660,711 

Relevant academic research and scientific papers

Process for unsymmetrical dithioacetals and dithioketals

This invention relates to a novel process for preparing unsymmetrical dithioacetals and dithioketals from aryl aldehydes and ketones.

ASYMMETRIC DITHIOACETALS III: THE PREPARATION OF THE ENANTIOMERS OF 3-((((3-(2-(7-CHLOROQUINOLIN-2-YL)-(E)-ETHENYL)PHENYL)-3-DIMETHYLAMINO-3-OXOPROPYLTHIO)METHYL)THIO)PROPIONIC ACID (L-660,711) (MK-571), AN ANTAGONIST OF LEUKOTRIENE D4

The application of a novel method for the preparation of chiral dithioacetals to the synthesis of the enantiomers of L-660,711, an antagonist of leukotriene D4, is described.Reaction of 3-(t-butyldiphenylsilyloxymethyl)benzaldehyde or isophthal