115104-46-6

Upstream product

• 79-37-8 oxalyl dichloride 
• 3966-32-3 (R)-methoxyphenylacetic acid 
• 34713-98-9 (R)-(-)-α-methoxyphenylacetyl chloride 

Downstream Products

• 124573-23-5 (R)-Methoxy-phenyl-thioacetic acid S-[(2-dimethylcarbamoyl-ethylsulfanyl)-(3-formyl-phenyl)-methyl] ester 
• 130066-18-1 3-[(R)-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-((R)-2-methoxy-2-phenyl-acetylsulfanyl)-methylsulfanyl]-propionic acid methyl ester 
• 130066-19-2 3-[(S)-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-((R)-2-methoxy-2-phenyl-acetylsulfanyl)-methylsulfanyl]-propionic acid methyl ester 
• 123059-32-5 (R)-Methoxy-phenyl-thioacetic acid S-[(R)-tert-butylsulfanyl-(4-chloro-phenyl)-methyl] ester 
• 123059-33-6 (R)-Methoxy-phenyl-thioacetic acid S-[(S)-tert-butylsulfanyl-(4-chloro-phenyl)-methyl] ester 
• 115104-48-8 (R)-Methoxy-phenyl-thioacetic acid S-[[3-(tert-butyl-diphenyl-silanyloxymethyl)-phenyl]-(2-dimethylcarbamoyl-ethylsulfanyl)-methyl] ester 
• 115104-48-8 (R)-Methoxy-phenyl-thioacetic acid S-[[3-(tert-butyl-diphenyl-silanyloxymethyl)-phenyl]-(2-dimethylcarbamoyl-ethylsulfanyl)-methyl] ester 
• 123059-30-3 (R)-Methoxy-phenyl-thioacetic acid S-[(R)-(2-dimethylcarbamoyl-ethylsulfanyl)-(3-methoxy-phenyl)-methyl] ester 
• 123059-31-4 (R)-Methoxy-phenyl-thioacetic acid S-[(S)-(2-dimethylcarbamoyl-ethylsulfanyl)-(3-methoxy-phenyl)-methyl] ester 

Relevant academic research and scientific papers

ASYMMETRIC DITHIOACETALS III: THE PREPARATION OF THE ENANTIOMERS OF 3-((((3-(2-(7-CHLOROQUINOLIN-2-YL)-(E)-ETHENYL)PHENYL)-3-DIMETHYLAMINO-3-OXOPROPYLTHIO)METHYL)THIO)PROPIONIC ACID (L-660,711) (MK-571), AN ANTAGONIST OF LEUKOTRIENE D4

The application of a novel method for the preparation of chiral dithioacetals to the synthesis of the enantiomers of L-660,711, an antagonist of leukotriene D4, is described.Reaction of 3-(t-butyldiphenylsilyloxymethyl)benzaldehyde or isophthal

2-substituted quinoline dioic acids and pharmaceutical compositions

Compounds having the formula: STR1 are antagonists of leukotrienes and inhibitors of their biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents.

ASYMMETRIC DITHIOACETALS II: A NOVEL AND VERSATILE METHOD FOR THE PREPARATION OF CHIRAL DITHIOACETALS

Reaction of aldehydes with one equivalent each of a thiol and a chiral thioacid such as (R)-(-)-α-methoxyphenylthiolacetic acid in the presence of an acidic catalyst such as ZnI2 or p-toluenesulfonic acid yields diastereomeric mixed thioacetals in good yi

2-Substituted quinoline dioic acids

Compounds having the formula: are antagonists of leukotrienes and inhibitors of their biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents.