115118-06-4

Upstream product

• 94670-94-7 6-bromobenzo-1,3-dioxol-5-yl 3,4,5-trimethoxyphenyl ketone 
• 75-05-8 acetonitrile 

Downstream Products

• 115140-86-8 (E)-3-(6-Bromo-benzo[1,3]dioxol-5-yl)-3-(3,4,5-trimethoxy-phenyl)-acrylonitrile 
• 107377-38-8 trans-2-(3,4,5-trimethoxyphenyl)benzocyclobutyl acetate 
• 107377-32-2 2-(3,4,5-Trimethoxy-phenyl)-1,2-dihydro-4,6-dioxa-cyclobuta[f]indene-1-carboxylic acid ethyl ester 
• 110087-30-4 3-(6-Bromo-benzo[1,3]dioxol-5-yl)-3-(3,4,5-trimethoxy-phenyl)-propionitrile 
• 107377-30-0 3-(6-Bromo-benzo[1,3]dioxol-5-yl)-3-(3,4,5-trimethoxy-phenyl)-propionic acid ethyl ester 
• 104715-43-7 (1S,2R)-2-(3,4,5-Trimethoxy-phenyl)-1,2-dihydro-4,6-dioxa-cyclobuta[f]inden-1-ol 
• 94671-22-4 trans-5,6-dihydro-6-(3,4,5-trimethoxyphenyl)cyclobuta(f)-1,3-benzodioxolecarboxylic acid 
• 104715-45-9 (E)-4-[(1R,2S)-2-(3,4,5-Trimethoxy-phenyl)-1,2-dihydro-4,6-dioxa-cyclobuta[f]inden-1-yloxycarbonylamino]-but-2-enoic acid 
• 104715-44-8 (E)-4-[(1R,2S)-2-(3,4,5-Trimethoxy-phenyl)-1,2-dihydro-4,6-dioxa-cyclobuta[f]inden-1-yloxycarbonylamino]-but-2-enoic acid methyl ester 
• 104759-83-3 (4aR,5R,6S,11bS)-2-Oxo-6-(3,4,5-trimethoxy-phenyl)-3,4,4a,5,6,11b-hexahydro-2H-1,8,10-trioxa-3-aza-cyclopenta[b]phenanthrene-5-carboxylic acid methyl ester 
• 104715-47-1 (4aS,5S,6S,11bS)-2-Oxo-6-(3,4,5-trimethoxy-phenyl)-3,4,4a,5,6,11b-hexahydro-2H-1,8,10-trioxa-3-aza-cyclopenta[b]phenanthrene-5-carboxylic acid methyl ester 

Relevant academic research and scientific papers

A Highly Stereoselective Synthesis of Podophyllotoxin and Analogues Based on an Intramolecular Diels-Alder Reaction

A synthesis of podophyllotoxin and several analogues is described.The key step that generates all four chiral centers of podophylotoxin involves an intramolecular Diels-Alder reaction between an appropriately substituted o-quinodimethane and a pendant cro