1151397-50-0Relevant academic research and scientific papers
Synthesis of substituted 1-benzazepin-2-ones via ring-closing olefin metathesis
Hoyt, Scott B.,London, Clare,Park, Min
, p. 1911 - 1913 (2009)
The 1-benzazepin-2-one ring system is an important structural feature of marketed drugs, clinical candidates, and other bioactive molecules. We have developed a new benzazepinone synthesis that employs ring-closing olefin metathesis as a key step. This route provides efficient access to substituted benzazepinones that are difficult to synthesize via existing procedures.
