115237-38-2

Basic information

• Product Name: C₁₁H₁₂BrNO₂
• Synonyms: C₁₁H₁₂BrNO₂
• CAS NO: 115237-38-2
• Molecular Weight: 270.126
• Mol File: 115237-38-2.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: C₁₁H₁₂BrNO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₁H₁₂BrNO₂(115237-38-2)
• EPA Substance Registry System: C₁₁H₁₂BrNO₂(115237-38-2)

Safety Data

• Hazardous Substances Data: 115237-38-2(Hazardous Substances Data)

Upstream product

• 1450-75-5 5-Bromo-2-hydroxyacetophenone 
• 68-12-2 N,N-dimethyl-formamide 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 1836-05-1 3’-bromo-2’-hydroxylacetophenone 

Downstream Products

• 942474-12-6 6-bromo-3-iodo-4H-chromen-4-one 
• 1384665-19-3 4-bromo-2-{2-methyl-6-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]pyrazolo[1,5-a]pyrimidin-7-yl}-phenol 
• 115237-39-3 3,6-dibromo-4H-1-benzopyran-4-one 
• 1349177-77-0 C₁₆H₁₁BrO₂ 
• 51483-92-2 6-bromo-1-benzopyran-4(4H)-one 
• 213690-27-8 4-bromo-2-(isoxazol-5-yl)phenol 
• 1345115-95-8 dimethyl 4-(4-phenylbiphenylcarbonyl)biphenyl-2,3-dicarboxylate 

Relevant articles and documents

Visible Light-Promoted Selenylation/Cyclization of Enaminones toward the Formation of 3-Selanyl-4H-Chromen-4-Ones

A simple and efficient visible-light-promoted selenylation/cyclization of enaminones have been realized for the practical synthesis of 3-selanyl-4H-chromen-4-ones. This reaction is performed in the mild conditions, no transition metal catalyst or photocatalysts and no additional oxidants are required. In addition, the 3-selanyl-4H-chromen-4-ones could be easily converted to selanyl-functionalized pyrimidines by reacting with benzamidine substrates. (Figure presented.).

T3P mediated domino C(sp2)-H sulfenylation/annulation of enaminones and methylsulfinyls for the synthesis of chromone thioether derivatives

A new regioselective method for the synthesis of 3-(methylthio)-4H-chromen-4-one and 3-(phenylthio)-4H-chromen-4-one derivatives has been developed. The reaction between o-hydroxy-phenyl-functionalized enaminones and methylsulfinyl derivatives using T3P gave good yields of chromone thioether derivatives. The reaction proceeds via domino chromone ring construction and C(sp2)-H bond sulfenylation under transition-metal-free conditions.

Selectfluor-Mediated Tandem Cyclization of Enaminones for the Synthesis of 3-Fluorochromones

An efficient synthesis of various 3-fluorochromones (3-fluoro-4 H -chromene-4-ones) from enamino ketones by using Selectfluor is described. The key step in the synthesis involves tandem fluorination and cyclization to form 3-fluorochromones in good yields. The significant features of this method include simple operational procedures, a high purity of the product, and excellent regioselectivity.