1152440-02-2Relevant articles and documents
COMPOSITIONS FOR INHIBITING UBIQUITIN SPECIFIC PROTEASE 1
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Paragraph 00169, (2020/07/15)
This disclosure relates to modulating ubiquitin specific protease 1 (USP1) and provides novel chemical compounds useful as inhibitors of USP1, as well as various uses of these compounds. USP1 inhibiting compounds are useful in the treatment of diseases and disorders associated with USP1, such as cancer.
Long-acting dipeptidyl peptidase-IV inhibitor, application and preparation method of intermediate thereof
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Paragraph 0098; 0101, (2017/08/02)
The invention relates to a long-acting dipeptidyl peptidase-IV inhibitor, an application and a preparation method of an intermediate thereof, and in particular to a compound of formula (I) as shown in the specification, a preparation method of the compound, an application of the compound in treating and preventing diabetes, particularly DPP-4 related diseases of Type-II diabetes, and a medicinal composition and a medicinal preparation containing the compound of the formula (I) as shown in the specification, wherein the definitions of symbols in the formula are identical to those in the specification.
PHTHALAZINONE KETONE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL USE THEREOF
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Paragraph 0109; 0111, (2013/06/28)
A phthalazinone ketone derivative as represented by formula (I), a preparation method thereof, a pharmaceutical composition containing the derivative, a use thereof as a poly (ADP-ribose) polymerase (PARP) inhibitor, and a cancer treatment method thereof.
PHTHALAZINONE KETONE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL USE THEREOF
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Paragraph 0156; 0157, (2013/06/04)
A phthalazinone ketone derivative as represented by formula (I), a preparation method thereof, a pharmaceutical composition containing the derivative, a use thereof as a poly (ADP-ribose) polymerase (PARP) inhibitor, and a cancer treatment method thereof are described.
TETRAHYDRO-IMIDAZOY1,5-A¨PYRAZINE DERIVATIVES, PREPARATION METHODS AND MEDICAL USES THEREOF
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Page/Page column 46, (2010/10/03)
Tetrahydro-imidazo[1,5-a]pyrazine derivatives of formula ( I ), their preparation methods, pharmaceutical compositions containing the derivatives and uses thereof as medicaments, especially as dipeptidyl peptidase IV inhibitor, wherein the substituents of formula ( I ) are defined as same as the description.