1152478-57-3Relevant articles and documents
First-in-class, dual-action, 3,5-disubstituted indole derivatives having human nitric oxide synthase (nNOS) and norepinephrine reuptake inhibitory (NERI) activity for the treatment of neuropathic pain
Mladenova, Gabriela,Annedi, Subhash C.,Ramnauth, Jailall,Maddaford, Shawn P.,Rakhit, Suman,Andrews, John S.,Zhang, Dongqin,Porreca, Frank
experimental part, p. 3488 - 3501 (2012/06/17)
A family of different 3,5-disubstituted indole derivatives having 6-membered rings were designed, synthesized, and demonstrated inhibition of human nitric oxide synthase (NOS) with norepinephrine reuptake inhibitory activity (NERI). The structure-activity