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1-[2-METHOXYPHENYL]-4-[4-(2-PHTHALIMIDO)-BUTYL]PIPERAZINE HYDROCHLORIDE, also known as NAN-190, is a hydrobromide compound derived from the reaction of NAN 190 with one equivalent of hydrobromic acid. It is characterized by its potent antagonistic activity against the serotonin SR-1A receptor, making it a significant compound in the field of pharmaceuticals and neuroscience.

115338-32-4

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115338-32-4 Usage

Uses

Used in Pharmaceutical Industry:
1-[2-METHOXYPHENYL]-4-[4-(2-PHTHALIMIDO)-BUTYL]PIPERAZINE HYDROCHLORIDE is used as a serotonin SR-1A antagonist for its ability to block the serotonin receptor, which can be beneficial in the treatment of various neurological and psychiatric disorders. Its antagonistic properties allow it to modulate the serotonin signaling pathways, potentially leading to improved therapeutic outcomes in conditions such as depression, anxiety, and other mood disorders.
Used in Research and Development:
In the field of research and development, 1-[2-METHOXYPHENYL]-4-[4-(2-PHTHALIMIDO)-BUTYL]PIPERAZINE HYDROCHLORIDE serves as a valuable tool for studying the role of serotonin receptors in various biological processes. Its potent antagonistic activity enables researchers to investigate the underlying mechanisms of serotonin-related disorders and develop novel therapeutic strategies targeting the serotonin system.
Used in Drug Delivery Systems:
Similar to gallotannin, 1-[2-METHOXYPHENYL]-4-[4-(2-PHTHALIMIDO)-BUTYL]PIPERAZINE HYDROCHLORIDE can also be incorporated into drug delivery systems to enhance its bioavailability, delivery, and therapeutic efficacy. By employing various organic and metallic nanoparticles as carriers, the compound can be more effectively targeted to specific cells or tissues, potentially improving its overall effectiveness in treating serotonin-related disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 115338-32-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,3,3 and 8 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 115338-32:
(8*1)+(7*1)+(6*5)+(5*3)+(4*3)+(3*8)+(2*3)+(1*2)=104
104 % 10 = 4
So 115338-32-4 is a valid CAS Registry Number.
InChI:InChI=1/C23H27N3O3.BrH/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28;/h2-5,8-11H,6-7,12-17H2,1H3;1H

115338-32-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name NAN 190 hydrobromide

1.2 Other means of identification

Product number -
Other names 1-(2-Methoxyphenyl)-4-[4-(2-phthalimido)butyl]piperazine hydrobromide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:115338-32-4 SDS

115338-32-4Downstream Products

115338-32-4Relevant academic research and scientific papers

An efficient synthesis of aripiprazole, buspirone and NAN-190 by the reductive alkylation of amines procedure

Kowalski, Piotr,Jaskowska, Jolanta

experimental part, p. 81 - 85 (2012/04/10)

The reductive alkylation of amines procedure was applied for the synthesis of aripiprazole 1a, buspirone 1b, and NAN-190 1c. The reductive alkylation of amines procedure was applied for the synthesis of aripiprazole 1a, buspirone 1b, and NAN-190 1c. Copyright

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