1153380-07-4Relevant academic research and scientific papers
NOVEL BENZIMIDAZOLE COMPOUND
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Paragraph 0091-0093, (2017/04/03)
PROBLEM TO BE SOLVED: To provide a compound having safety and storage stability which can be commercially practical as an active ingredient of a therapeutic agent for a neurodegenerative disease and the like, and a pharmaceutical composition comprising th
NEW CRYSTAL OF BENZIMIDAZOLE COMPOUND, AND PRODUCTION METHOD THEREOF
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Paragraph 0076, (2018/10/10)
PROBLEM TO BE SOLVED: To provide a new crystal of 2-[2-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-benzimidazole-5-yl]-1,3- benzoxazole having excellent storage stability capable of maintaining the same quality, when being stored as a pharmaceutical technical
Direct synthesis of a pde4 inhibitor by using pd-cu-catalyzed c-h/c-br coupling of benzoxazole with a heteroaryl bromide
Kuroda, Kiichi,Tsuyumine, Shinjiro,Kodama, Tomohiro
, p. 1053 - 1058 (2017/01/16)
A short and practical synthetic route of a PDE4 inhibitor (1) was established by using Pd-Cu-catalyzed C-H/ C-Br coupling of benzoxazole with a heteroaryl bromide. The combination of Pd(OAc)2-Cu(OTf)2-PPh3 was found to be
AGENT FOR TREATMENT OR PREVENTION OF DISEASES ASSOCIATED WITH ACTIVITY OF NEUROTROPHIC FACTORS
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Page/Page column 52, (2012/04/17)
A compound depicted by the formula below, or a pharmaceutically acceptable salt or solvate thereof. wherein, R1 represents (1) a C3-6 alkyl group,(2) a C1-6 alkyl group substituted with one or more substituent group(s) sel
