1153668-78-0

Basic information

• Product Name: 2-hydrazino-3-(4-fluorophenyl)-1,8-naphthyridine
• Synonyms: 2-hydrazino-3-(4-fluorophenyl)-1,8-naphthyridine
• CAS NO: 1153668-78-0
• Molecular Weight: 254.267
• Mol File: 1153668-78-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-hydrazino-3-(4-fluorophenyl)-1,8-naphthyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydrazino-3-(4-fluorophenyl)-1,8-naphthyridine(1153668-78-0)
• EPA Substance Registry System: 2-hydrazino-3-(4-fluorophenyl)-1,8-naphthyridine(1153668-78-0)

Safety Data

• Hazardous Substances Data: 1153668-78-0(Hazardous Substances Data)

Upstream product

• 60467-61-0 2-amino-3-(4-fluorophenyl)-1,8-naphthyridine 
• 459-22-3 4-fluorophenylacetonitrile 
• 1082429-86-4 2-chloro-3-(4-fluorophenyl)-1,8-naphthyridine 
• 1082429-76-2 1,2-dihydro-3-(4-fluorophenyl)-1,8-naphthyridin-2-one 
• 7521-41-7 2-Aminonicotinaldehyde 

Downstream Products

• 1153668-29-1 C₂₇H₁₉FN₄O 
• 1345691-36-2 C₂₁H₁₃FN₄ 
• 1345691-37-3 C₂₂H₁₅FN₄ 
• 1345691-29-3 C₂₂H₁₇FN₄ 
• 1345691-32-8 C₂₁H₁₄ClFN₄ 
• 1345691-40-8 C₂₁H₁₂ClFN₄ 
• 1345691-31-7 C₂₁H₁₄ClFN₄ 
• 1345691-39-5 C₂₁H₁₂ClFN₄ 
• 1345691-33-9 C₂₁H₁₄FN₅O₂ 
• 1345691-41-9 C₂₁H₁₂FN₅O₂ 
• 1345691-34-0 C₂₁H₁₄FN₅O₂ 
• 1345691-42-0 C₂₁H₁₂FN₅O₂ 
• 1345691-28-2 C₂₁H₁₅FN₄ 
• 1345691-30-6 C₂₂H₁₇FN₄O 

Relevant articles and documents

Green synthesis and antibacterial activity of 3-aryl-4-formyl-1-[3-(4- fluorophenyl)-1,8- naphthyridin-2-yl]pyrazoles

An efficient and convenient method for the synthesis of 3-aryl- 4-formyl-1-[3-(4-fluorophenyl)-1,8-naphthyridin-2-yl]-pyrazoles 4 from acetophenone 3-(4-fluorophenyl)-1,8-naphthyridin-2- ylhydrazones 3 is achieved using POCl3-DMF over silica gel under microwave irradiation. The structural assignments of compounds 3 and 4 are based on their elemental analyses and spectral (IR, 1H NMR and MS) data. The compounds 4 have been screened for their antibacterial activity.

Green synthesis of 1,2,4-triazolo[4,3-a][1,8]naphthyridines using PhI(OAc)2-Al2O3 under microwave irradiation

Alumina-supported iodobenzene diacetate [PhI(OAc)2-Al 2O3] is a highly efficient reagent for the oxidative cyclization of N-arylidene-N′-[3-(4-fluorophenyl)-[1,8]naphthyridin-2-yl]- hy-drazines 7 to 1-aryl-4-[4-fluoro phenyl]-1,2,4-triazolo[4,3-a][1,8] naphthyridines 8 in solvent-free conditions under microwave irradiation. The products are obtained in good yields and excellent purities. The structural assignments of compounds 3-8 were based on their spectral (IR, 1H NMR and MS) and analytical data.