1154057-94-9

Upstream product

• 766-98-3 1-ethynyl-4-fluorobenzene 
• 124-38-9 carbon dioxide 
• 2687-12-9 cinnamyl chloride 

Downstream Products

• 1258518-62-5 9-(4-fluorophenyl)-3a,4-dihydronaphtho[2,3-c]furan-1(3H)-one 
• 1154057-80-3 1-(2-(2-cinnamylphenyl)ethynyl)-4-fluorobenzene 

Relevant academic research and scientific papers

Ordered Mesoporous CeO2-supported Ag as an Effective Catalyst for Carboxylative Coupling Reaction Using CO2

Ag/Mesoporous CeO2 (Ag/M?CeO2) catalysts were synthesized through the gas bubbling-assisted membrane reduction (GBMR) method and characterized by XRD, ICP-OES, N2 adsorption-desorption, XPS, Raman spectroscopy, TEM, HRTEM, HAADF-STEM and CO2-TPD. Ag/M?CeO2 catalysts contain uniform mesoporous structure, large surface area and oxygen vacancies, which promote the dispersion of Ag nanoparticles. Density functional theory (DFT) calculations indicate that Ag nanoparticles supported on M?CeO2 could facilitate the formation of oxygen vacancies, which result in higher CO2 adsorption capacity. With the most oxygen vacancies and the well-dispersed Ag active species, Ag (3.12 %)/M?CeO2 exhibits high efficiency for the carboxylative coupling of terminal alkynes, chloride compounds and CO2 under mild reaction conditions (60 °C, 0.5 MPa), affording a wide range of functionalized 2-alkynoates in good yields.

Development of magnesium oxide-silver hybrid nanocatalysts for synergistic carbon dioxide activation to afford esters and heterocycles at ambient pressure

Multi-metallic hybrid nanocatalysts consisting of a porous metal oxide host and metal satellite guests serve as a scaffold for multi-step transformations of divergent and energy-challenging substrates. Here we have developed a 3D porous MgO framework (Lewis basic host) with Ag0 nanoparticles (noble metal guest) for ambient pressure activation and insertion of CO2 into unsaturated alkyne substrates. The hybrid MgO@Ag-x (x = 2, 5, 7, 8 at% Ag) catalysts are synthesized by impregnating Ag+ ions in porous MgO cubes followed by reduction using NaBH4. Morphological (SEM, TEM, EDX mapping) and structural (PXRD, XPS) characterization reveal that the micron-sized hybrid cubes derive from self-assembly of ～100 nm (edge length) MgO cubes decorated with ～5 to 25 nm Ag0 NPs. Detailed XPS analysis illustrates Ag0 is present in two forms, 2 into aryl alkynes followed by SN2 coupling with allylic chlorides to afford a wide range of ester and lactone heterocycles in excellent yields (61-93%) and with low E-factor (2.8). The proposed mechanism suggests a CO2 capture and substrate assembly role for 3D porous MgO while Ag0 performs the key activation of alkyne and CO2 insertion steps. The catalyst is recyclable (5×) with no significant loss of product yield. Overall, these results demonstrate viable approaches to hybrid catalyst development for challenging conversions such as CO2 utilization in a green and sustainable manner.

Ligand-free Ag(I)-catalyzed carboxylative coupling of terminal alkynes, chloride compounds, and CO2

Simple silver(I) slats were found to be highly efficient and selective catalyst for carboxylative coupling of aryl- or alkyl-substituted terminal alkynes, CO2, and various allylic, propargylic or benzylic chlorides to exclusively yield function