115424-06-1

Basic information

• Product Name: Toluene-4-sulfonic acid (S)-2-benzyloxycarbonylamino-3-(4-methoxy-phenyl)-propyl ester
• Synonyms: Toluene-4-sulfonic acid (S)-2-benzyloxycarbonylamino-3-(4-methoxy-phenyl)-propyl ester
• CAS NO: 115424-06-1
• Molecular Weight: 469.558
• Mol File: 115424-06-1.mol

Chemical Properties

• CAS DataBase Reference: Toluene-4-sulfonic acid (S)-2-benzyloxycarbonylamino-3-(4-methoxy-phenyl)-propyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Toluene-4-sulfonic acid (S)-2-benzyloxycarbonylamino-3-(4-methoxy-phenyl)-propyl ester(115424-06-1)
• EPA Substance Registry System: Toluene-4-sulfonic acid (S)-2-benzyloxycarbonylamino-3-(4-methoxy-phenyl)-propyl ester(115424-06-1)

Safety Data

• Hazardous Substances Data: 115424-06-1(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 53796-61-5 N-acetyl-O-methyl-tyrosine 
• 6330-11-6 O-methyl-L-tyrosine ethyl ester; hydrochloride 
• 6230-11-1 O-Methyltyrosine 
• 115424-04-9 N-benzyloxycarbonylamino-3-(4-methoxyphenyl)propionic acid ethyl ester 
• 16679-94-0 N-[(phenylmethoxy)carbonyl]-L-tyrosine 
• 949-67-7 L-tyrosine ethyl ester 
• 115424-05-0 (S)-benzyl (1-hydroxy-3-(4-methoxyphenyl)propan-2-yl)carbamate 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 50505-80-1 l-para-Methoxyamphetamine hydrochloride 
• 621-84-1 O-benzyl carbamate 
• 140-67-0 Estragole 
• 115424-07-2 [(S)-1-Iodomethyl-2-(4-methoxy-phenyl)-ethyl]-carbamic acid benzyl ester 

Relevant articles and documents

Asymmetric synthesis of unnatural amino acids and tamsulosin chiral intermediate

An efficient and enantioselective hydrogenation of N-acetylamino phenyl acrylic acids was successfully developed by using ruthenium catalyst. This methodology is important in the field of pharmaceuticals and provides a new process for the preparation of unnatural amino acids and tamsulosin chiral intermediate.

A simple and efficient procedure for the synthesis of optically active 4-methoxy-α-methylphenylethylamine from tyrosine

Optically active 4-methoxy-α-methylphenylethylamine (1), a useful chiral building block in medicinal chemistry, was synthesized from L- or D- tyrosine by using a simple and efficient procedure via one-pot zinc reduction of the corresponding O-tosylate (4) in the presence of H2O and NaI in pure form.