1154740-80-3

Basic information

• Product Name: 5-Chloro-3-chromanone
• Synonyms: 5-Chloro-3-chromanone;5-ChlorochroMan-3-one
• CAS NO: 1154740-80-3
• Molecular Formula: C9H7ClO2
• Molecular Weight: 182.60368
• Mol File: 1154740-80-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-Chloro-3-chromanone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloro-3-chromanone(1154740-80-3)
• EPA Substance Registry System: 5-Chloro-3-chromanone(1154740-80-3)

Safety Data

• Hazardous Substances Data: 1154740-80-3(Hazardous Substances Data)

Usage

General Description

5-Chloro-3-chromanone, also known as 5-Chloro-3H-chromen-4-one, is a chemical compound with the molecular formula C9H7ClO2. It is a chlorinated derivative of 3-chromanone, which is a heterocyclic ketone. 5-Chloro-3-chromanone is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used in the production of dyes and pigments. 5-Chloro-3-chromanone has a pale yellow color and is soluble in various organic solvents. It is important to handle this compound with care as it may be harmful if swallowed, inhaled, or absorbed through the skin.

Upstream product

• 53600-33-2 6-methoxyanthranilic acid 
• 54166-96-0 methyl 2-amino-6-methoxybenzoate 
• 18362-30-6 2-chloro-6-hydroxybenzaldehyde 
• 29866-54-4 2-chloro-6-methoxybenzaldehyde 
• 1154740-78-9 C₁₀H₆ClNO 
• 1038726-89-4 2-chloro-6-methoxyphenylmethanol 
• 936479-46-8 methyl 6-chloro-2-methoxybenzoate 
• 1154740-79-0 C₁₀H₇ClO₃ 

Relevant articles and documents

Preparation method of 5-chloro pyran derivative

The invention discloses a preparation method of 5-chloro pyran derivative, namely 5-chloro-N-methyl-3,4-dihydro-2H-pyran-3-amine. The preparation method comprises the following steps of using 2-(6-chloro-2-hydroxy phenyl)methyl acetate as an initial raw material; performing etherifying, ring closing, decarboxylating and ammonia reduction reaction, so as to obtain a target product 5. The preparation method has the advantage that a wide variety of compound bases can be synthesized by using the product as template micromolecules.

INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION

Compounds of formula (I): wherein R4, R6 and R7 are defined herein, are useful as inhibitors of HIV replication.

INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION

The present invention relates to compounds of formula (I) wherein c, X, Y, R2, R3, R4 and R6 are as defined herein, compositions and uses thereof for treating human immunodeficiency virus (HIV) infection. In particular, the present invention provides novel inhibitors of HIV integrase, pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HIV infection