115476-98-7Relevant academic research and scientific papers
Facile synthesis of α, β-unsaturated esters through a one-pot copper-catalyzed aerobic oxidation-Wittig reaction
Ren, Cheng,Shi, Zhenyu,Ding, Weijie,Liu, Zhiqing,Jin, Huile,Yu, Xiaochun,Wang, Shun
supporting information, p. 14 - 17 (2017/12/06)
An efficient one-pot synthesis of α, β-unsaturated esters through the aerobic oxidation – Wittig tandem reaction of alcohols and phosphorous ylide is developed. This new method operates under mild reaction conditions, and uses CuI/TEMPO (TEMPO = 2,2,6,6-tetramethylpiperidine-N-oxyl) as co-catalyst and air (O2) as the oxidant. It tolerates a wide range of functionalized benzylic alcohol and aliphatic alcohols.
Highly selective reactions of unbiased alkenyl halides and alkylzinc halides: Negishi-plus couplings
Krasovskiy, Arkady,Lipshutz, Bruce H.
supporting information; experimental part, p. 3822 - 3825 (2011/09/20)
High yielding stereo- and chemoselective Pd-catalyzed cross-couplings in THF at room temperature of alkenyl iodides and bromides with primary and secondary alkyl zinc iodides have been developed with the aid of N-methyimidazole as the key additive.
Z-selective horner-wadsworth-emmons-type reaction using a 10-P-5 phosphorane bearing bidentates derived from 1-naphthol
Kojima, Satoshi,Arimura, Jun-Ya,Kajiyama, Kazumasa
experimental part, p. 1138 - 1139 (2011/02/28)
A Horner-Wadsworth-Emmons-type 10-P-5 phosphorane reagent bearing bidentate ligands from 1-naphthol was prepared and examined in the olefination of aldehydes. Z-Selectivity was generally high except for the case of 3-phenylpropanal, and acetophenone was a
Highly (E)-selective wadsworth-emmons reactions promoted by methylmagnesium bromide
Claridge, Timothy D. W.,Davies, Stephen G.,Lee, James A.,Nicholson, Rebecca L.,Roberts, Paul M.,Russell, Angela J.,Smith, Andrew D.,Toms, Steven M.
supporting information; experimental part, p. 5437 - 5440 (2009/06/18)
(Chemical Equation Presented) An experimentally simple protocol for the very highly (E)-selective Wadsworth-Emmons reaction [(E):(Z) selectivities in excess of 180:1 in some cases] of a range of straight-chain and branched aliphatic, substituted aromatic, and base-sensitive aldehydes via reaction with an alkyl diethylphosphonoacetate and MeMgBr is reported.
Effect of Microwave Irradiation on the Direction and Stereochemistry of Rodionov and Michael Reactions
Romanova,Gravis,Kudan,Leshcheva,Zyk
, p. 692 - 697 (2007/10/03)
The reactions of 2-phenylpropanal with ethyl hydrogen malonate and benzylamine (or benzyl-ammonium acetate) and of ethyl 4-phenyl-2-pentenoate with benzylamine take different pathways, depending on the conditions.
