115492-15-4Relevant academic research and scientific papers
Synthesis of 5-(Acylethynyl)uracils and their Corresponding 2'-Deoxyribonucleosides through Palladium-catalysed Reactions
Kundu, Nitya G.,Dasgupta, Swapan K.
, p. 2657 - 2664 (2007/10/02)
Good yields of the title uracils were obtained by using the palladium-catalysed reaction between 5-iodo-2,4-dimethoxypyrimidine and substituted propargylic alcohols rather than the corresponding ketones.The same strategy works for coupling with the 5-iodo
Synthesis of Dimethoxypyrimidines and Uracils with Novel C-5 Substituents
Kundu, Nitya G.,Chaudhuri, Lakshmi
, p. 1677 - 1682 (2007/10/02)
5-Iodo-2,4,-dimethoxypyrimidine 1 on treatment with copper(I) 3-tetrahydropyran-2-yloxyprop-1-ynide was converted into 2,4-dimethoxy-5-(3-tetrahydropyran-2-yloxyprop-1-ynyl)pyrimidine 2 which on treatment with toluene-p-sulphonic acid in methanol led to 5
Synthesis and Biological Activities of Novel 5-(2-Acylethynyl)uracils
Kundu, Nitya G.,Das, Biswajit,Spears, C. Paul,Majumdar, Anjali,Kang, Sang-Ihn
, p. 1975 - 1979 (2007/10/02)
5-(2-Acylethynyl)-2,4-dimethoxypyrimidines (3-6) were synthesized in excellent yields from 2,4-dimethoxy-5-pyrimidine (2) by treatment with acid chlorides in the presence of anhydrous aluminum chloride.Compounds 3-6 were deblock
A General Procedure for the Synthesis of Dimethoxypyrimidines and Uracils with Highly Functionalised C-5 Substituents
Kundu, Nitya G.,Choudhuri, Lakshmi N.,Das, Biswajit
, p. 1165 - 1166 (2007/10/02)
A versatile method for the synthesis of 5--2,4-dimethoxypyrimidines (5)-(13), 5-(2-acyl-ethynyl)2,4-dimethoxypyrimidines (14)-(22), 5-(2-acyl-chlorovinyl)uracils (23)-(27) and 5-(2-acylethynyl)uracils (28)-(30) is d
