1155363-96-4Relevant articles and documents
A direct route to 2-alkyl-4-carbethoxy-5-vinyloxazoles
Zhang, Jianmin,Ciufolini, Marco A.
supporting information; experimental part, p. 4699 - 4701 (2010/09/20)
The reaction of an α-chloroglycinate ester with the dimethylaluminum acetylide derivative of phenyl propargyl ether provides the corresponding 5-vinyloxazole in 40-50% yield.
Development of an oxazole conjunctive reagent and application to the total synthesis of siphonazoles
Zhang, Jianmin,Polishchuk, Elena A.,Chen, Jie,Ciufolini, Marco A.
experimental part, p. 9140 - 9151 (2010/03/01)
(Chemical Equation Presented) The preparation of 4-carbethoxy-5-methyl-2- (phenylsulfonyl)methyloxazole and its use in the elaboration of more complex oxazoles are described. A total synthesis of the unique natural products siphonazoles A and B, illustrates an application of this building block. A discussion of the biological activity of the siphonazoles is also presented.