115541-05-4

Basic information

• Product Name: 2-(p-ethoxyphenylamino)-4-(2'-pyrazinyl)thiazole
• CAS NO: 115541-05-4
• Molecular Weight: 298.368
• Mol File: 115541-05-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(p-ethoxyphenylamino)-4-(2'-pyrazinyl)thiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(p-ethoxyphenylamino)-4-(2'-pyrazinyl)thiazole(115541-05-4)
• EPA Substance Registry System: 2-(p-ethoxyphenylamino)-4-(2'-pyrazinyl)thiazole(115541-05-4)

Safety Data

• Hazardous Substances Data: 115541-05-4(Hazardous Substances Data)

Upstream product

• 19847-10-0 pyrazinoyl chloride 
• 91516-39-1 2-(α-chloroacetyl)pyrazine 
• 880-29-5 1-(4-ethoxyphenyl)thiourea 

Relevant articles and documents

Synthesis and Antitubercular Activity of 4-(5-Nitro-2-furyl/2-pyrazinyl/1-adamantyl)-2-(alkyl/aryl/arylamino)thiazoles

The reaction of haloketones, obtained from Arndt-Eistert reaction on the acid chlorides of 1-adamantane, 5-nitrofuroic acid and pyrazine-2-carboxylic acid, with different thioamides and thioureas affords the title thiazoles (I-III).Some of them exhibit interesting antitubercular activity at 6.25 to 0.38 μg/ml concentration against H37Rv strain of M. tubercolosis in vitro testing.The structure activity relationship (SAR) has also been discussed.