1155702-72-9Relevant academic research and scientific papers
Scaled-up Negishi-coupling of aryl halides bearing unprotected amides with Knochel-type organozinc reagents
Xiong, Jia-Chao,Xu, Wan,Dong, Zhi-Bing
, p. 569 - 570 (2017)
Without the need of any protecting groups, aryl halides bearing acidic amides were coupled with several Knochel-type organozinc reagents by using Pd(OAc)2 as catalyst and 2-dicyclohexylphosphino-2',6'-dimethoxy biphenyl (S-Phos) as ligand. The reactions were carried out on a large scale (30 mmol), furnishing the desired coupling products smoothly in excellent yields (70–98%).
LiCl-mediated preparation of functionalized benzylic indium(III) halides and highly chemoselective palladium-catalyzed cross-coupling in a protic cosolvent
Chen, Yi-Hung,Sun, Mai,Knochel, Paul
supporting information; experimental part, p. 2236 - 2239 (2009/08/14)
(Chemical Equation Presented) Sensitive functional groups such as COR, CHO, or CH2OH can be present in benzylic indium reagents prepared by the direct insertion of indium in the presence of LiCl. These reagents undergo palladium-catalyzed cross
