115580-40-0Relevant academic research and scientific papers
PALLADIUM CATALYZED ALLYLIC C-ALKYLATION OF HIGHLY ACIDIC AND ENOLIC HETEROCYCLIC SUBSTRATES: TETRONIC ACID AND TRIACETIC ACID LACTONE
Moreno-Manas, Marcial,Prat, Maria,Ribas, Jordi,Virgili, Albert
, p. 581 - 584 (1988)
Tetronic acid (pKa 3.76) and triacetic acid lactone (pKa 4.94) have been alkylated at their active carbon atoms by means of thermodinamically controlled palladium catalyzed allylic alkylations.
PALLADIUM CATALYZED C-ALLYLATION OF HIGHLY ACIDIC CARBO AND HETEROCYCLIC β-DICARBONYL COMPOUNDS
Prat, M.,Moreno-Manas, M.,Ribas, J.
, p. 7205 - 7212 (2007/10/02)
Highly acidic carbo and heterocyclic β-dicarbonyl compounds such as barbituric acid, 3,5-dimethyl-2H-1,2,6-thiadiazine 1,1-dioxide, cyclohexane-1,3-dione, tetronic acids, Meldrum acid and 1,2-diphenylpyrazolidine-3,5-dione are efficiently C-allylated with primary and secondary allylating agents under palladium catalysis.
