115580-73-9

Upstream product

• 115580-67-1 6-Allyl-1,1,4,4-tetramethyl-1,2,3,4-tetrahydro-naphthalene 
• 115580-68-2 2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-ylmethyl)-oxirane 
• 27452-17-1 6-bromo-1,2,3,4-tetrahydro-1,1,4,4-tetramethylnaphthalene 
• 115580-72-8 4-Hydroxymethyl-3-[2-hydroxy-3-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propyl]-benzoic acid 
• 74-88-4 methyl iodide 
• 115580-70-6 1-[2,5-Bis-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-phenyl]-3-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propan-2-ol 
• 115580-71-7 1-Oxo-3-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-ylmethyl)-isochroman-6-carboxylic acid 
• 115580-69-3 2,2'-(2-bromo-1,4-phenylene)bis(4,4-dimethyl-4,5-dihydrooxazole) 
• 13815-89-9 2-bromobenzene-1,4-dicarbonyl dichloride 

Relevant academic research and scientific papers

AROMATIC RETINOIDS: A SHORT SYNTHESIS OF 7-HYDROXY-6-(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPHTHYL)-2-NAPHTHOIC ACID, (7-HYDROXY-TTNN).

7-hydroxy-TTNN, a possible metabolite of the aromatic retinoid: 6-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-2-naphthoic acid (TTNN) (2) was synthesized through a short route, the key step of which was a one pot oxidation / cyclisation / aromatis