13815-89-9

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule of the compound.

Explanation

The compound is derived from benzene, a basic building block in organic chemistry.

Explanation

It is a compound that is used in chemical reactions to produce other compounds but is not the final product itself.

Explanation

The compound may pose risks to human health and must be handled with care in industrial settings.

Explanation

Due to its potential health hazards, proper handling and safety protocols are necessary when working with 1,4-BENZENEDICARBONYL DICHLORIDE,2-BROMO- in an industrial setting.

Derivative of benzene

Yes

Common uses

a. Manufacturing of polymers (nylon, polyester)
b. Production of various chemicals and materials
c. Synthesis of pharmaceuticals, agrochemicals, and specialized chemicals

Reactive intermediate

Yes

Health hazards

Potential health hazards

Industrial handling

Requires care and safety measures

Upstream product

• 7697-26-9 3-bromo-4-methylbenzoic acid 
• 553-94-6 4-bromo-m-xylene 
• 586-35-6 2-bromo-1,4-benzenedicarboxylic acid 

Downstream Products

• 154239-21-1 diethyl 2-Bromoterephthalate 
• 115580-70-6 1-[2,5-Bis-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-phenyl]-3-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propan-2-ol 
• 1186377-08-1 dimethyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1,4-dicarboxylate 
• 1221343-14-1 1-(hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)carboxylic acid 
• 1214921-69-3 2,2'-(2-bromo-1,4-phenylene)bis(5-methyloxazole) 
• 1214921-99-9 2,2'-(2-bromo-1,4-phenylene)bis(5-methylene-4,5-dihydrooxazole) 
• 1365620-54-7 (E)-[1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)-3-p-tolyl]propenone 
• 1365620-94-5 (E)-[1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)-3-(4-amino-3-methoxyphenyl)]propenone 
• 1365620-93-4 (E)-[1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)-3-(3-methoxy-4-nitrophenyl)]propenone 
• 1365620-86-5 (E)-[1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)-3-(3,4-dihydroxyphenyl)]propenone 
• 1365620-85-4 (E)-[1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)-3-(3-hydroxyphenyl)]propenone 
• 1365620-84-3 (E)-[1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)-3-(2-hydroxyphenyl)]propenone 
• 1365620-83-2 (E)-[3-(3-aminophenyl)1-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)]propenone 

Relevant academic research and scientific papers

Photoactivatable Fluorophore for Stimulated Emission Depletion (STED) Microscopy and Bioconjugation Technique for Hydrophobic Labels

The use of photoactivatable dyes in STED microscopy has so far been limited by two-photon activation through the STED beam and by the fact that photoactivatable dyes are poorly solvable in water. Herein, we report ONB-2SiR, a fluorophore that can be both

Identification and Structure-Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli

In Gram-negative bacteria, efflux pumps are able to prevent effective cellular concentrations from being achieved for a number of antibiotics. Small molecule adjuvants that act as efflux pump inhibitors (EPIs) have the potential to reinvigorate existing antibiotics that are currently ineffective due to efflux mechanisms. Through a combination of rigorous experimental screening and in silico virtual screening, we recently identified novel classes of EPIs that interact with the membrane fusion protein AcrA, a critical component of the AcrAB-TolC efflux pump in Escherichia coli. Herein, we present initial optimization efforts and structure-activity relationships around one of those previously described hits, NSC 60339 (1). From these efforts we identified two compounds, SLUPP-225 (17h) and SLUPP-417 (17o), which demonstrate favorable properties as potential EPIs in E. coli cells including the ability to penetrate the outer membrane, improved inhibition of efflux relative to 1, and potentiation of the activity of novobiocin and erythromycin.

Intracellular Protein-Labeling Probes for Multicolor Single-Molecule Imaging of Immune Receptor-Adaptor Molecular Dynamics

Single-molecule imaging (SMI) has been widely utilized to investigate biomolecular dynamics and protein-protein interactions in living cells. However, multicolor SMI of intracellular proteins is challenging because of high background signals and other lim

Fluorescent Rhodamines and Fluorogenic Carbopyronines for Super-Resolution STED Microscopy in Living Cells

A range of bright and photostable rhodamines and carbopyronines with absorption maxima in the range of λ=500-630 nm were prepared, and enabled the specific labeling of cytoskeletal filaments using HaloTag technology followed by staining with 1 μm solution

BENZOXABOROLE FUNGICIDES

Compounds of formula (I) are as defined in the claims, and their use in compositions and methods for the control and/or prevention of microbial infection, particularly fungal infection, in plants and to processes for the preparation of these compounds.

Aminocarbonyl compounds, Preparing method thereof and amide side chain liquid crystal polymer using the same

The present invention relates to an aminocarbonyl styrene compound, a preparation method for the same, and an amide side chain liquid crystalline polymer thereof. More specifically, the aminocarbonyl styrene compound is used as an intermediate to prepare

Red Si-rhodamine drug conjugates enable imaging in GFP cells

Here we evaluated a series of Si-derivatized rhodamine (SiR) dyes for their ability to visualize a model drug in live cells. We show that a charge neutral SiR derivative (but not others) can indeed be used to follow the intracellular location of the model therapeutic drug in GFP cells. This journal is the Partner Organisations 2014.

Cell Permeable, Fluorescent Dye

The invention pertains to a near-infrared fluorescent dye that is cell permeable and can be attached to selected proteins in living cells. The dye has the general formula or its corresponding spirolactone wherein Y is chosen from the group consisting of S

Aminoacidic units wired on poly(aryleneethynylene) platforms as highly selective mercury-responsive materials

Novel highly ethynylated materials carrying aminoacidic side arms on poly(aryleneethynylene) (PAE) conjugated backbones have been prepared and fully characterized. The luminescent sensing properties of these materials toward metal ions were investigated.

CELL PERMEABLE, FLUORESCENT DYE

The invention pertains to a near-infrared fluorescent dye that is cell permeable and can be attached to selected proteins in living cells. The dye has the general formula (I) or its or its corresponding spirolactone (II) wherein Y is chosen from the group