1155847-42-9

Basic information

• Product Name: 2-Bromo-4-chloro-3-fluoropyridine
• Synonyms: 2-Bromo-4-chloro-3-fluoropyridine
• CAS NO: 1155847-42-9
• Molecular Formula: C5H2BrClFN
• Molecular Weight: 210.4314832
• Mol File: 1155847-42-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 205.4±35.0 °C(Predicted)
• Appearance: /
• Density: 1.829±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -1.13±0.10(Predicted)
• CAS DataBase Reference: 2-Bromo-4-chloro-3-fluoropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-4-chloro-3-fluoropyridine(1155847-42-9)
• EPA Substance Registry System: 2-Bromo-4-chloro-3-fluoropyridine(1155847-42-9)

Safety Data

• Hazardous Substances Data: 1155847-42-9(Hazardous Substances Data)

Usage

Description

2-Bromo-4-chloro-3-fluoropyridine is a heterocyclic organic compound with the molecular formula C5H2BrClFNO. It features a pyridine ring with bromine, chlorine, and fluorine substituents on different positions, making it a versatile intermediate in the synthesis of pharmaceuticals and agrochemicals. Its unique structure and reactivity contribute to its value in the development of new chemical compounds for medicinal and agricultural applications.

Uses

Used in Pharmaceutical Industry:
2-Bromo-4-chloro-3-fluoropyridine is used as a key intermediate for the synthesis of various drugs. Its presence in the molecular structure allows for the creation of complex molecules with potential therapeutic effects, making it an essential component in the development of new pharmaceuticals.
Used in Agrochemical Industry:
2-Bromo-4-chloro-3-fluoropyridine is used as a building block in the production of agricultural chemicals. Its ability to form stable and effective compounds makes it a valuable asset in the synthesis of pesticides, herbicides, and other agrochemicals that are crucial for crop protection and yield enhancement.

Upstream product

• 2546-56-7 4-chloro-3-fluoro-pyridine 

Downstream Products

• 1155847-43-0 4-chloro-3-fluoropicolinonitrile 
• 1155847-45-2 tert-butyl [3-(3-bromo-5-chlorophenoxy)-4-chloropyridin-2-yl]carbamate 
• 1155847-44-1 3-(3-bromo-5-chlorophenoxy)-4-chloropyridine-2-carboxylic acid 
• 1155847-61-2 3-(3-bromo-5-chlorophenoxy)-4-chloropyridine-2-carbonitrile 
• 1155846-78-8 C₁₉H₁₂Cl₂N₆O₂ 
• 1155847-49-6 C₁₂H₅Cl₃N₂O₂ 
• 1155846-77-7 3-chloro-5-{[4-chloro-2-oxo-1-(1H-pyrazolo[3,4-b]pyridin-3-ylmethyl)-1,2-dihydropyridin-3-yl]oxy}benzonitrile 
• 1155847-48-5 3-chloro-5-[(4-chloro-2-hydroxypyridin-3-yl)oxy]benzonitrile 
• 1155847-46-3 3-[(2-amino-4-chloropyridin-3-yl)oxy]-5-chlorobenzonitrile 

Relevant articles and documents

NOVEL MACROCYCLES AS FACTOR XIA INHIBITORS

The present invention provides compounds of Formula (Ia): or a stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.

NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS

Heteroaromatic compounds of Formula (I), are HIV reverse transcriptase inhibitors, wherein ring A is: (ii-a), (ii-b), (ii-c), (ii-d), or (ii-e); and wherein n, L, M, U, X, Y, Z, RE, RF, R1, R2A, R2B,