1155847-45-2

Upstream product

• 2546-56-7 4-chloro-3-fluoro-pyridine 
• 1155847-43-0 4-chloro-3-fluoropicolinonitrile 
• 1155847-42-9 2-bromo-4-chloro-3-fluoropyridine 
• 1155847-44-1 3-(3-bromo-5-chlorophenoxy)-4-chloropyridine-2-carboxylic acid 
• 75-65-0 tert-butyl alcohol 

Downstream Products

• 1155847-46-3 3-[(2-amino-4-chloropyridin-3-yl)oxy]-5-chlorobenzonitrile 
• 1155847-48-5 3-chloro-5-[(4-chloro-2-hydroxypyridin-3-yl)oxy]benzonitrile 
• 1155846-77-7 3-chloro-5-{[4-chloro-2-oxo-1-(1H-pyrazolo[3,4-b]pyridin-3-ylmethyl)-1,2-dihydropyridin-3-yl]oxy}benzonitrile 
• 1155847-49-6 C₁₂H₅Cl₃N₂O₂ 
• 1155846-78-8 C₁₉H₁₂Cl₂N₆O₂ 

Relevant academic research and scientific papers

Design and synthesis of pyridone inhibitors of non-nucleoside reverse transcriptase

Next generation NNRTIs are sought which possess both broad spectrum antiviral activity against key mutant strains and a high genetic barrier to the selection of new mutant viral strains. Pyridones were evaluated as an acyclic conformational constraint to

NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS

Heteroaromatic compounds of Formula (I), are HIV reverse transcriptase inhibitors, wherein ring A is: (ii-a), (ii-b), (ii-c), (ii-d), or (ii-e); and wherein n, L, M, U, X, Y, Z, RE, RF, R1, R2A, R2B,