1156-74-7

Basic information

• Product Name: 3-(4-chlorophenyl)-2-(ethylsulfanyl)-4(3H)-quinazolinone
• Synonyms: 3-(4-chlorophenyl)-2-(ethylsulfanyl)-4(3H)-quinazolinone
• CAS NO: 1156-74-7
• Molecular Formula: C₁₆H₁₃ClN₂OS
• Molecular Weight: 316.80522
• Mol File: 1156-74-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(4-chlorophenyl)-2-(ethylsulfanyl)-4(3H)-quinazolinone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-chlorophenyl)-2-(ethylsulfanyl)-4(3H)-quinazolinone(1156-74-7)
• EPA Substance Registry System: 3-(4-chlorophenyl)-2-(ethylsulfanyl)-4(3H)-quinazolinone(1156-74-7)

Safety Data

• Hazardous Substances Data: 1156-74-7(Hazardous Substances Data)

Upstream product

• 75-03-6 ethyl iodide 
• 1028-40-6 3-(4-chlorophenyl)-2-thioxo-2,3-dihydro-1H-quinazolin-4-one 

Downstream Products

• 100822-31-9 3-(4-chlorophenyl)-2-ethylsulfonylquinazolin-4-one 
• 95241-44-4 3-amino-2-[(4-chlorophenyl)amino]-4(3H)-quinazolinone 

Relevant articles and documents

Synthesis, properties, and mass-spectrometric fragmentation of 2-thio derivatives of 3-arylquinazolin-4-ones

We have studied the reactions of alkylation, oxidation, and hydrolysis of 3-aryl-2-thioxoquinazolin-4-ones. Alkylation in an alkaline medium occurs exclusively at the sulfur atom. Oxidation by hydrogen peroxide leads to formation of 3-arylquinazoline-2,4-diones. The latter are also obtained in base or acid hydrolysis of the synthesized S-alkyl derivatives. When 3-aryl-2-thioxoquinazolin-4-ones are reacted with iodine, we obtain the disulfides, while the reaction with chlorine in hydrochloric acid leads to 2-chloroquinazolin-4-ones. Studying the mass spectrometric behavior of the compounds obtained made it possible to observe in the gas phase ring-chain isomerization of the heterocyclic ring, and also S-N migration of the propargyl radical in molecular ions of the S-propargyl derivatives.