115699-51-9Relevant academic research and scientific papers
Anti-bacterial cephalosporin compounds
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, (2008/06/13)
There are presented anti-bacterial cephalosporins having broad antimicrobial activity of the formula STR1 wherein R1 is an antibiotically active quinolonyl; R2 is selected from the group consisting of hydrogen, lower alkoxy, amino, l
Cephalosporin 3'-Quinolone Esters with a Dual Mode of Action
Albrecht, Harry A.,Beskid, George,Chan, Ka-Kong,Christenson, James G.,Cleeland, Roy,et al.
, p. 77 - 86 (2007/10/02)
According to the generally accepted mechanism by which bacterial enzymes react with cephalosporins, opening of the β-lactam ring can lead to the expulsion of a 3'-substituent.A series of dual-action cephalosporins was prepared in which antibacterial quino
