115802-71-6Relevant academic research and scientific papers
Highly regioselective indoline synthesis under nickel/photoredox dual catalysis
Tasker, Sarah Z.,Jamison, Timothy F.
supporting information, p. 9531 - 9534 (2015/08/18)
Nickel/photoredox catalysis is used to synthesize indolines in one step from iodoacetanilides and alkenes. Very high regioselectivity for 3-substituted indoline products is obtained for both aliphatic and styrenyl olefins. Mechanistic investigations indic
Formation of N-acetyl-2,3-dihydroindoles by the electrochemical cleavage of the carbon-chlorine bond in N-allyl-2-chloroacetanilides
Dias, Marylene,Gibson, Mandy,Grimshaw, James,Hill, Ian,Trocha-Grimshaw, Jadwiga,Hammerich, Ole
, p. 549 - 554 (2007/10/03)
The electrochemically induced radical cyclization of N-allyl-2-chloroacetanilides to form N-acetyl-2,3-dihydroindoles has been demonstrated where the phenyl ring contains an electron withdrawing substituent such as cyano. Cyclization of N-allyl-2-chloroacetanilide was successful in the presence of (E)-stilbene as electron transfer agent yielding 1-acetyl-3-methyl-2,3-dihydroindole. Indirect electrochemical reduction of N-cinnamyl-2-chloroacetanilide leads mainly to cleavage of the cinnamyl group and only a low yield of N-acetyl-3-benzyl-2,3-dihydroindole was obtained. Acta Chemica Scandinavica 1998.
INTRAMOLECULAR RADICAL CYCLIZATION REACTIONS. AN APPROACH TO THE INDOLE ALKALOIDS
Dittami, James P.,Ramanatham, Halasya
, p. 45 - 48 (2007/10/02)
The intramolecular radical cyclization reaction of N-allyl substituted derivates of o-bromoacetanilide provides a short and effective route to a variety of dihydroindole systems.
