115818-50-3Relevant articles and documents
Decarboxylative aldol reaction of α,α-difluoro-β-ketocarboxylate salt: A facile method for generation of difluoroenolate
Tarui, Atsushi,Oduti, Mayuna,Shinya, Susumu,Sato, Kazuyuki,Omote, Masaaki
, p. 20568 - 20575 (2018/06/14)
We developed a decarboxylative aldol reaction using α,α-difluoro-β-ketocarboxylate salt, carbonyl compounds, and ZnCl2/N,N,N′,N′-tetramethylethylenediamine. The generation of difluoroenolate proceeded smoothly under mild heating to provide α,α-
Mg0-promoted selective C-F bond cleavage of trifluoromethyl ketones: A convenient method for the synthesis of 2,2-difluoro enol silanes
Amii, Hideki,Kobayashi, Takeshi,Hatamoto, Yasushi,Uneyama, Kenji
, p. 1323 - 1324 (2007/10/03)
2,2-difluoro enol silyl ethers were readily prepared by Mg0 promoted selective defluorination of trifluoromethyl ketones in the presence of TMSCI, which involves C-F bond cleavage.
ZINC-COPPER(I) CHLORIDE OR -SILVER(I) ACETATE PROMOTED ALDOL REACTION OF CHLORODIFLUOROMETHYL KETONES WITH CARBONYL COMPOUNDS. A GENERAL AND EFFECTIVE ROUTE TO α,α-DIFLUORO-β-HYDROXY KETONES
Kuroboshi, Manabu,Ishihara, Takashi
, p. 6481 - 6484 (2007/10/02)
Chlorodifluoromethyl ketones efficiently underwent the aldol reaction with a variety of aldehydes or ketones in the presence of zinc, a catalytic amount of copper(I) chloride or silver(I) acetate, and molecular sieves to give the corresponding α,α-difluor
