115886-91-4Relevant academic research and scientific papers
SYNTHETIC METHODS FOR THE PREPARATION OF BASIC D- AND L-PSEUDO-SUGARS. SYNTHESIS OF CARBOCYCLIC ANALOGUES OF N-ACETYL-MURAMYL-L-ALANYL-D-ISOGLUTAMINE (MDP)
Barton, Derek H. R.,Augy-Dorey, S.,Camara, J.,Dalko, P.,Delaumeny, J. M.,et al.
, p. 215 - 230 (2007/10/02)
Two exocyclic olefins 10 and 22, readily elaborated from D-glucosamine, have been transformed by Ferrier rearrangement reaction into aminocyclohexanones 11, 12 and 23, 24.Reduction of ketone 11 with tri-t-butoxy-aluminium hydride followed by sequential ac
Synthesis of Biologically Active Carbocyclic Analogues of N-Acetylmuramyl-L-alanyl-D-isoglutamine (MDP)
Barton, Derek H. R.,Camara, Jose,Dalko, Peter,Gero, Stephen D.,Quiclet-Sire, Beatrice,Stuetz, Peter
, p. 3764 - 3766 (2007/10/02)
Two biologically active analogues of MDP containing pseudo-D-glucosamine have been synthesised using as key step the Ferrier rearrangement (carbohydrate inosose).Several different procedures for carrying out this reaction have been compared.
