1159516-46-7

Basic information

• Product Name: 2-(4'-bromo-3'-fluorophenyl)-1,3-benzoxazole
• Synonyms: 2-(4'-bromo-3'-fluorophenyl)-1,3-benzoxazole
• CAS NO: 1159516-46-7
• Molecular Weight: 292.107
• Mol File: 1159516-46-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4'-bromo-3'-fluorophenyl)-1,3-benzoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4'-bromo-3'-fluorophenyl)-1,3-benzoxazole(1159516-46-7)
• EPA Substance Registry System: 2-(4'-bromo-3'-fluorophenyl)-1,3-benzoxazole(1159516-46-7)

Safety Data

• Hazardous Substances Data: 1159516-46-7(Hazardous Substances Data)

Upstream product

• 95-55-6 2-amino-phenol 
• 153556-42-4 4-bromo-3-fluorobenzoic acid 
• 273-53-0 benzoxazole 
• 631912-19-1 3-bromo-4-fluorobenzene-1-sulfonyl chloride 

Downstream Products

• 1352918-29-6 5-[4''-(benzo[d]oxazol-2'''-yl)-2''-fluorophenyl]-2'-deoxyuridine 
• 1352918-22-9 2-(4'-pinacolatoboronyl-3'-fluorophenyl)-1,3-benzoxazole 

Relevant articles and documents

Palladium-catalyzed desulfitative C-arylation of a benzo[d]oxazole C-H bond with arene sulfonyl chlorides

A palladium-catalyzed direct desulfitative C-arylation of a benzo[d]oxazole C-H bond with arene sulfonyl chlorides is described. The procedure tolerates halo, cyano, nitro, trifluoromethyl, acetyl and acetylamino groups on the phenyl ring of sulfonyl chlorides, providing the arylation products in moderate to good yields. It represents a practical and attractive alternative for the synthesis of 2-aryl benzoxazoles.