115967-47-0

Basic information

• Product Name: phenyl 3,4,5-trimethoxybenzoate
• Synonyms: phenyl 3,4,5-trimethoxybenzoate
• CAS NO: 115967-47-0
• Molecular Formula: C₁₆H₁₆O₅
• Molecular Weight: 288.29524
• Mol File: 115967-47-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: phenyl 3,4,5-trimethoxybenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: phenyl 3,4,5-trimethoxybenzoate(115967-47-0)
• EPA Substance Registry System: phenyl 3,4,5-trimethoxybenzoate(115967-47-0)

Safety Data

• Hazardous Substances Data: 115967-47-0(Hazardous Substances Data)

Upstream product

• 4521-61-3 3,4,5-Trimethoxybenzoyl chloride 
• 108-95-2 phenol 
• 42543-45-3 3,4,5-trimethoxybenzoyl azide 
• 3291-03-0 3,4,5-trimethoxybenzohydrazide 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 98-80-6 phenylboronic acid 

Downstream Products

• 99265-10-8 1-phenyl-3-(3,4,5-trimethoxyphenyl)-1,3-propanedione 

Relevant articles and documents

Transition-Metal-Free Poly(thiazolium) Iodide/1,8-Diazabicyclo[5.4.0]undec-7-ene/Phenazine-Catalyzed Esterification of Aldehydes with Alcohols

Poly(3,4-dimethyl-5-vinylthiazolium) iodide was used as a polymer precatalyst in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) and phenazine for the oxidative esterification of aldehydes with alcohols. Selective functionalization of OH groups was achieved in the presence of NH2 groups. The poly(thiazolium) iodide/DBU/phenazine system exhibited excellent catalytic activity and could be reused five times without loss of activity.

N-heterocyclic carbene-catalyzed aerobic oxidative direct esterification of aldehydes with organoboronic acids

A simple procedure affording benzoates through a NHC-catalyzed aerobic oxidative esterification of aldehydes with organoboronic acids has been disclosed. This process allows access to a wide variety of aromatic esters in good to excellent yields under simple, efficient, and sustainable reaction conditions (see scheme).

Palladium-catalyzed aerobic oxidative coupling of acyl chlorides with arylboronic acids

The first example of a palladium-catalyzed aerobic oxidative coupling of acyl chlorides with arylboronic acids has been developed, leading to a wide range of aryl benzoates in good to excellent yields. This catalytic system shows broad functional group tolerance. Preliminary mechanistic experiments using deuterium labeling showed that the oxygen atom was derived from dioxygen. Copyright

A practical synthesis of dibenzoylmethanes

Dibenzoylmethanes are easily prepared in two steps starting from acetophenones, phenol and benzoyl chlorides. The phenyl benzoate is obtained by condensation of benzoyl chloride with phenol in a classical way. Stirring of the phenyl benzoate and acetophenone in DMSO with powdered sodium hydroxide during a few minutes gave the dibenzoylmethanes in yields depending on substituents on the phenyl rings.