1159706-84-9

Upstream product

• 1485-70-7 N-benzylbenzamide 
• 1609460-35-6 N-benzyl-N′-(4-fluorophenyl)benzimidamide 
• 46721-83-9 N-(chloro(phenyl)methylene)(phenyl)methanamine 
• 93-98-1 N-phenyl benzoyl amide 
• 366-75-6 N-(4-fluorophenyl)benzamide 
• 2106-02-7 2-chloro-4-fluoroaniline 
• 871907-34-5 N-(2-chloro-4-fluorophenyl)benzamide 
• 98-88-4 benzoyl chloride 
• 1402938-86-6 (Z)-N-(2-chloro-4-fluorophenyl)benzimidoyl chloride 
• 100-46-9 benzylamine 

Relevant academic research and scientific papers

Solvent/oxidant-switchable synthesis of multisubstituted quinazolines and benzimidazoles via metal-free selective oxidative annulation of arylamidines

A fast and simple divergent synthesis of multisubstituted quinazolines and benzimidazoles was developed from readily available amidines, via iodine(III)-promoted oxidative C(sp3)-C(sp2) and C(sp 2)-N bond formation in nonpolar and polar solvents, respectively. Further selective synthesis of quinazolines in polar solvent was realized by TEMPO-catalyzed sp3C-H/sp2C-H direct coupling of the amidine with K2S2O8 as the oxidant. No metal, base, or other additives were needed.

Palladium-catalyzed synthesis of benzimidazoles and quinazolinones from common precursors

N-(o-Halophenyl)imidoyl chlorides and the corresponding imidates are easily prepared and can be utilized as complementary precursors for the synthesis of important heterocycles. The synthesis of N-substituted benzimidazoles was possible from the palladium