115978-84-2Relevant academic research and scientific papers
DEFINITE TOTAL SYNTHESIS OF COUMARINOLIGNANS, DAPHNETICIN AND ITS REGIOISOMER
Tanaka, Hitoshi,Ishihara, Masaya,Ichino, Kazuhiko,Ito, Kazuo
, p. 3115 - 3122 (2007/10/02)
The synthesis of 7-benzyloxy-8-hydroxycoumarin (5) and 8-benzyloxy-7-hydroxycoumarin (11) was described and further, by use of 5 as a starting material, daphneticin (1) was synthesized.On the other hand, its regioisomer (2) was also synthesized from (8), readily prepared via two steps from 5, according to the method described in the synthesis of daphneticin.
