65535-50-4Relevant academic research and scientific papers
First enantioselective synthesis of daphneticin and its regioisomer
Ren, Xinfeng,Chen, Xiaochuan,Peng, Kun,Xie, Xingang,Xia, Yamu,Pan, Xinfu
, p. 1799 - 1804 (2007/10/03)
An enantioselective total synthesis of chiral daphneticin and its regioisomer is reported for the first time.
DEFINITE TOTAL SYNTHESIS OF COUMARINOLIGNANS, DAPHNETICIN AND ITS REGIOISOMER
Tanaka, Hitoshi,Ishihara, Masaya,Ichino, Kazuhiko,Ito, Kazuo
, p. 3115 - 3122 (2007/10/02)
The synthesis of 7-benzyloxy-8-hydroxycoumarin (5) and 8-benzyloxy-7-hydroxycoumarin (11) was described and further, by use of 5 as a starting material, daphneticin (1) was synthesized.On the other hand, its regioisomer (2) was also synthesized from (8), readily prepared via two steps from 5, according to the method described in the synthesis of daphneticin.
Synthesis of Apigravin
Raizada, M. B.,Garg, S. K.,Gupta, S. R.
, p. 918 - 919 (2007/10/02)
Apigravin (V), a new prenylated coumarin, isolated from the seeds of Apium graveolens, has been synthesised starting from 7,8-dihydroxycoumarin (I).The coumarin (I) on partial benzylation followed by methylation and catalytic debenzylation gives 7-hydroxy-8-methoxycoumarin (IV), which on prenylation yields the title compound (V), identical with a natural sample of apigravin.
