116-37-0

Basic information

• Product Name: 1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol
• Synonyms: 1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol;1,1'-(Isopropylidenebis[p-phenyleneoxy]) di-2-propanol;Isopropylidenediphenoxypropanol;2-Propanol, 1,1-(1-methylethylidene)bis(4,1-phenyleneoxy)bis-;2,2-BIS(4-HYDROXYPHENYL)PROPANEBIS(2-HYDROXYPROPYL)ETHER;2,2-BIS(4-(2-HYDROXY-PROPOXY)PHENYL)PROPANE;Bisphenol-A-propoxylat;1,1'-((1-methylethylidene)bis(4,1-phenyleneoxy))bis-2-propano
• CAS NO: 116-37-0
• Molecular Formula: C₂₁H₂₈O₄
• Molecular Weight: 284.3496
• EINECS: 204-137-9
• Mol File: 116-37-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 505℃
• Flash Point: 260℃
• Appearance: /
• Density: 1.102
• Vapor Pressure: 0Pa at 20℃
• PKA: 14.05±0.20(Predicted)
• Water Solubility: 109mg/L at 20℃
• CAS DataBase Reference: 1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol(116-37-0)
• EPA Substance Registry System: 1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol(116-37-0)

Safety Data

• Hazardous Substances Data: 116-37-0(Hazardous Substances Data)

Usage

Uses

Bisphenol A bis(2-hydroxypropyl) ether is an engineered material used as a coating for improved adhesion of aminoplasts to metals.

Flammability and Explosibility

Nonflammable

Synthetic route

diphenylolpropane diglycidyl ether (1675-54-3) → Bisphenol A propoxylate (116-37-0)

Conditions	Yield
With [carbonylchlorohydrido{bis[2-(diphenylphosphinomethyl)ethyl]amino}ethylamino] ruthenium(II); potassium tert-butylate; hydrogen In toluene at 75℃; under 37503.8 Torr; for 24h; regioselective reaction;	99%

BPA (80-05-7) + methyloxirane (75-56-9, 16033-71-9) → Bisphenol A propoxylate (116-37-0) + 4-(2-(4-(2-hydroxypropoxy)phenyl)propan-2-yl)phenol (57372-69-7) + BPA-3PO (210979-67-2)

Conditions	Yield
anion exchange resin A (OH-type) In 2-methoxy-ethanol at 100℃; for 6h;	A 99 %Chromat. B 0.1 %Chromat. C 0.8 %Chromat.

propylene glycol (57-55-6) + hydroquinone (123-31-9) → Bisphenol A propoxylate (116-37-0) + 2-(4-(2-(4-(2-hydroxypropoxy)phenyl)propan-2-yl)phenoxy)propan-1-ol (1003045-91-7)

Conditions	Yield
With sodium carbonate; urea; zinc(II) oxide at 170 - 190℃;

BPA (80-05-7) + methyloxirane (75-56-9, 16033-71-9) → Bisphenol A propoxylate (116-37-0)

Conditions	Yield
Stage #1: BPA With sodium hydroxide In tetrahydrofuran at 20℃; for 3h; Inert atmosphere; Stage #2: methyloxirane In tetrahydrofuran Inert atmosphere;

1,2-propylene cyclic carbonate (108-32-7) + BPA (80-05-7) → Bisphenol A propoxylate (116-37-0) + 2-(4-(2-(4-(2-hydroxypropoxy)phenyl)propan-2-yl)phenoxy)propan-1-ol (1003045-91-7)

Conditions	Yield
With potassium hydroxide Inert atmosphere; Heating;

Bisphenol A propoxylate (116-37-0) + 3-mercaptobutyric acid (26473-49-4) → 2,2-bis[4-{2-(3-mercaptobutyloyloxy)-2-methylethoxy}phenyl]propane

Conditions	Yield
With toluene-4-sulfonic acid In toluene at 140℃; for 4h;	95.1%

Bisphenol A propoxylate (116-37-0) → sulfuric acid mono-[1-methyl-2-(4-{1-methyl-1-[4-(2-sulfooxy-propoxy)-phenyl]-ethyl}-phenoxy)-ethyl] ester; compound with ammonia

Conditions	Yield
Stage #1: Bisphenol A propoxylate With pyridine; sulfuric acid; acetic anhydride at 50 - 55℃; for 0.5h; Stage #2: With ammonium hydroxide at 0℃; for 0.25h;

Bisphenol A propoxylate (116-37-0) + (E,E)-2-cyanohexa-2,4-dienoic acid (83697-84-1) → 2,2-Bis-[p-(2-(2-Cyano-2,4-hexadienoyl)-oxypropoxy)-phenyl]-propane (274695-40-8)

Conditions	Yield
With 2,6-di-tert-butyl-4-methyl-phenol In acetone

Bisphenol A propoxylate (116-37-0) + methyl (α-chloromethyl)acrylate (922-15-6) → C31H40O8

Conditions	Yield
Stage #1: Bisphenol A propoxylate With 2,6-di-tert-butyl-4-methyl-phenol; sodium hydride In tetrahydrofuran for 2h; Inert atmosphere; Stage #2: methyl (α-chloromethyl)acrylate In tetrahydrofuran at 20℃; Inert atmosphere;

Upstream product

• 1675-54-3 diphenylolpropane diglycidyl ether 
• 108-32-7 1,2-propylene cyclic carbonate 
• 80-05-7 BPA 
• 75-56-9 methyloxirane 
• 57-55-6 propylene glycol 
• 123-31-9 hydroquinone 

Downstream Products

• 274695-40-8 2,2-Bis-[p-(2-(2-Cyano-2,4-hexadienoyl)-oxypropoxy)-phenyl]-propane 

Relevant articles and documents

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