1160474-47-4 Usage
Cyclopropane derivative
The compound is based on a cyclopropane ring, which is a three-carbon ring with bond angles of 60 degrees, making it a strained and highly reactive structure.
Carboxylic acid functional group
The presence of a -COOH group in the molecule, which is a characteristic functional group of carboxylic acids, providing acidic properties and the ability to form hydrogen bonds.
Benzylamino carbonyl side chain
The molecule contains an amino group (-NH2) bonded to a phenyl ring (a benzene ring), which is referred to as a benzylamino group. This side chain adds complexity to the molecule and can participate in various chemical reactions and interactions.
Potential pharmacological importance
The compound has been studied for its potential as a therapeutic agent in the treatment of various diseases, indicating its possible use in medicine.
Building block in synthesis
Due to its unique structural features, 2-[(Benzylamino)carbonyl]-cyclopropanecarboxylic acid may be useful as a building block in the synthesis of other organic compounds, making it valuable in the field of chemistry.
Interesting target for research and development
The combination of its chemical properties and potential applications in medicine and chemistry make 2-[(Benzylamino)carbonyl]-cyclopropanecarboxylicacid a promising subject for further research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 1160474-47-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,6,0,4,7 and 4 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1160474-47:
(9*1)+(8*1)+(7*6)+(6*0)+(5*4)+(4*7)+(3*4)+(2*4)+(1*7)=134
134 % 10 = 4
So 1160474-47-4 is a valid CAS Registry Number.
1160474-47-4Relevant academic research and scientific papers
Enantioselective bacterial hydrolysis of amido esters and diamides derived from (±)-trans-cyclopropane-1,2-dicarboxylic acid
Hugentobler, Katharina G.,Rebolledo, Francisca
, p. 615 - 623 (2014/01/06)
Different optically active amido esters, mixed acid esters, amido acids, and diamides derived from trans-cyclopropane-1,2-dicarboxylic acid were prepared from the commercially available diethyl (±)-trans-cyclopropane-1,2- dicarboxylate. The key step was the Rhodococcus rhodochrous IFO 15564 catalyzed hydrolysis of the corresponding racemic amide. The amidase present in this microorganism showed moderate to high enantioselectivity towards these substrates. In addition a simple and efficient Curtius rearrangement of some of the enzymatically prepared cyclopropanecarboxylic acids allowed us to obtain optically active β-aminocyclopropanecarboxylic acid derivatives with high yields and enantiomeric excesses. The Royal Society of Chemistry.
Cyclopropane-derived peptidomimetics. Design, synthesis, evaluation, and structure of novel HIV-1 protease inhibitors
Martin, Stephen F.,Dorsey, Gordon O.,Gane, Todd,Hillier, Michael C.,Kessler, Horst,Baur, Matthias,Math?, Barbara,Erickson, John W.,Bhat, T. Nagarajan,Munshi, Sanjeev,Gulnik, Sergei V.,Topol, Igor A.
, p. 1581 - 1597 (2007/10/03)
Toward establishing the general efficacy of using trisubstituted cyclopropanes as peptide mimics to stabilize extended peptide structures, the cyclopropanes 20a-d were incorporated as replacements into 9-13, which are analogues of the known HIV-1 protease
