116072-39-0Relevant academic research and scientific papers
Catalytic asymmetric oxidation of sulfide with titanium-mandelic acid complex: Practical synthesis of (S)-3-[1-(2-methylphenyl)imidazol-2-ylsulfinyl]propan-1-ol, the key intermediate of OPC-29030
Matsugi,Fukuda,Muguruma,Yamaguchi,Minamikawa,Otsuka
, p. 2739 - 2744 (2001)
An effective catalytic asymmetric oxidation of prochiral sulfide 1a to (S)-2a has been achieved by the use of chiral titanium-mandelic acid complex. The enantioselectivity was found to be not influenced by moisture, and moderate to high selectivity (76% e
Reaction of Dimethyl N-Aryl- and N-Alkylcarbonimidodithioates with Aminoacetaldehyde Diethyl Acetal: A Direct Synthesis of 1-Aryl- and 1-Alkyl-2-methylthioimidazoles
Pooranchand, Dinah,Ila, Hiriyakkanavar,Junjappa, Hiriyakkanavar
, p. 1136 - 1138 (2007/10/02)
The reaction of dimethyl N-aryl- or N-alkylcarbonimidodithioates with aminoacetaldehyde diethyl acetal in refluxing acetic acid affords 1-aryl or 1-alkyl-2-methylthioimidazoles in good yields.Dimethyl N-isopropylcarbonimidodithioate gave 1-isopropylimidazole-2(3H)-thione under similar conditions.
