25372-14-9

Basic information

• Product Name: 1-(2-METHYLPHENYL)-1H-IMIDAZOLE-2-THIOL
• Synonyms: 2H-Imidazole-2-thione,1,3-dihydro-1-(2-methylphenyl)-
• CAS NO: 25372-14-9
• Molecular Formula: C₁₀H₁₀N₂S
• Molecular Weight: 190.27
• Mol File: 25372-14-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 289.5°Cat760mmHg
• Flash Point: 128.9°C
• Appearance: /
• Density: 1.27g/cm³
• Vapor Pressure: 0.0022mmHg at 25°C
• Refractive Index: 1.699
• CAS DataBase Reference: 1-(2-METHYLPHENYL)-1H-IMIDAZOLE-2-THIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-METHYLPHENYL)-1H-IMIDAZOLE-2-THIOL(25372-14-9)
• EPA Substance Registry System: 1-(2-METHYLPHENYL)-1H-IMIDAZOLE-2-THIOL(25372-14-9)

Safety Data

• Hazardous Substances Data: 25372-14-9(Hazardous Substances Data)

Usage

General Description

1-(2-Methylphenyl)-1H-imidazole-2-thiol is a chemical compound with the molecular formula C10H9NS. It is a heterocyclic compound containing both sulfur and nitrogen atoms in its structure. 1-(2-METHYLPHENYL)-1H-IMIDAZOLE-2-THIOL has potential applications in the synthesis of pharmaceuticals and agrochemicals due to its ability to act as a chelating ligand and its versatile reactivity. Additionally, it has shown potential biological activity, making it a subject of interest in medicinal chemistry research. Overall, 1-(2-Methylphenyl)-1H-imidazole-2-thiol is a versatile chemical with potential applications in various fields, including drug discovery and development.

InChI:InChI=1/C10H10N2S/c1-8-4-2-3-5-9(8)12-7-6-11-10(12)13/h2-7H,1H3,(H,11,13)

Upstream product

• 3129-90-6 isothiocyanic acid 
• 60185-84-4 3-aminopropionaldehyde dimethyl acetal 
• 614-69-7 2-tolyl isothiocyanate 

Downstream Products

• 116072-39-0 2-methylthio-1-o-tolyl-1H-imidazole 
• 161190-39-2 (+/-)-3,4-dihydro-6-<3-(1-o-tolyl-2-imidazolyl)sulfinylpropoxy>-2(1H)-quinolinone 
• 161190-55-2 (S)-3-(1-o-tolyl-1H-imidazol-2-ylsulfanyl)propan-1-ol 
• 173416-61-0 (R)-(+)-3,4-dihydro-6-<2-hydroxy-3-(1-o-tolyl-2-imidazolyl)thiopropoxy>-2(1H)-quinolinone 
• 161190-54-1 3-(1-o-tolyl-1H-imidazol-2-ylsulfanyl)propan-1-ol 
• 113857-31-1 3,4-dihydro-6-<3-(1-o-tolyl-2-imidazolyl)thiopropoxy>-2(1H)-quinolinone 

Relevant articles and documents

New bis(mercaptoimidazolyl)(pyrazolyl)borate ligands and their zinc complex chemistry

Nine new tripodal NS2 ligands of the bis(mercaptoimidazolyl)(pyrazolyl)borate type with varying 3-R-mercaptoimidazolyl moieties were prepared as their potassium salts. Treatment with zinc salts yielded the complex types L·Zn-Cl, L·Zn-I, L·Zn-ONO2, L·Zn-OClO3 and [L·Zn(imidazole)]ClO4. Attempts at the formation of L·Zn-OH or cationic L·Zn complexes resulted in dismutation and formation of ZnL2 complexes. Hydrolytic destruction yielded one [OZn4(thiooimidazolate)6] complex. The ZnS2NO coordination which is present in the enzyme-substrate complex of alcohol dehydrogenase could be successfully modelled by an [L·Zn(C2H5OH)]+ complex. The L·Zn-X complexes showed very low catalytic activity in the dehydrogenation of 2-propanol or the hydrogenation of p-nitrobenzaldehyde. The new compounds were identified by a total of 12 structure determinations. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.