1161004-77-8

Basic information

• Product Name: 2-(4-METHOXYPHENYL)-6-(TRIFLUOROMETHYL)-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE
• Synonyms: 2-(4-METHOXYPHENYL)-6-(TRIFLUOROMETHYL)-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE
• CAS NO: 1161004-77-8
• Molecular Formula: C₁₂H₁₁F₃N₂O₂
• Molecular Weight: 272.2231496
• Mol File: 1161004-77-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-METHOXYPHENYL)-6-(TRIFLUOROMETHYL)-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-METHOXYPHENYL)-6-(TRIFLUOROMETHYL)-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE(1161004-77-8)
• EPA Substance Registry System: 2-(4-METHOXYPHENYL)-6-(TRIFLUOROMETHYL)-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE(1161004-77-8)

Safety Data

• Hazardous Substances Data: 1161004-77-8(Hazardous Substances Data)

Usage

Chemical class

Heterocyclic compound

Explanation

It contains a ring structure with both carbon and non-carbon atoms, specifically nitrogen in this case.

Explanation

A derivative of pyridazinone, which is a heterocyclic compound with a core structure of a five-membered ring containing four carbon atoms and one nitrogen atom.

Explanation

The presence of a trifluoromethyl (CF3) group and a methoxyphenyl (ArOCH3) group contributes to the compound's unique chemical and pharmacological properties.

Explanation

The compound may exhibit various biological activities, making it a potential candidate for drug development in treating inflammation, pain, or cell proliferation-related diseases.

Explanation

The specific arrangement of carbon, nitrogen, and the functional groups mentioned above make this compound a subject of interest for medicinal and pharmaceutical research.

Derivative

Pyridazinone derivative

Functional groups

Trifluoromethyl group and methoxyphenyl group

Potential pharmaceutical applications

Anti-inflammatory, analgesic, or antiproliferative effects

Structural features

Unique arrangement of atoms and functional groups

Upstream product

• 22581-31-3 methyl 5,5,5-trifluoro-4-oxopentanoate 
• 3471-32-7 4-Methoxyphenylhydrazine 

Relevant articles and documents

Concise synthesis of ω-fluoroalkylated ketoesters. A building block for the synthesis of six-, seven-, and eight-membered fluoroalkyl substituted 1,2-diaza-3-one heterocycles

A concise and general synthetic route toward the small and medium-sized fluoroalkyl substituted 1,2-diaza-3-one heterocyclic ring skeletons via a sequential reaction of condensation and ring-closure reaction of ω-fluoroalkylated ketoesters 4 with hydrazin