116115-11-8

Basic information

• Product Name: Carbamic acid, [4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-[[(2,5-dioxo-1-pyrrolidinyl)oxy ]carbonyl]butyl]-, phenylmethyl ester, (S)-
• CAS NO: 116115-11-8
• Molecular Formula: C22H29N3O8
• Molecular Weight: 463.488
• Mol File: 116115-11-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-[[(2,5-dioxo-1-pyrrolidinyl)oxy ]carbonyl]butyl]-, phenylmethyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-[[(2,5-dioxo-1-pyrrolidinyl)oxy ]carbonyl]butyl]-, phenylmethyl ester, (S)-(116115-11-8)
• EPA Substance Registry System: Carbamic acid, [4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-[[(2,5-dioxo-1-pyrrolidinyl)oxy ]carbonyl]butyl]-, phenylmethyl ester, (S)-(116115-11-8)

Safety Data

• Hazardous Substances Data: 116115-11-8(Hazardous Substances Data)

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 7733-29-1 Z-Orn(Boc)-OH 

Downstream Products

• 116587-12-3 (2S,3aS,7aS)-1-[(R)-4-((S)-5-Amino-2-benzyloxycarbonylamino-pentanoylamino)-4-carboxy-butyryl]-octahydro-indole-2-carboxylic acid 
• 250215-13-5 (S)-2-{(S)-2-[(S)-2-(benzyloxycarbonylamino)-5-(tertbutoxycarbonylamino)valerylamino]-5-(tert-butoxycarbonylamino)valerylamino}-5-(tert-butoxycarbonylamino)valeric acid 
• 250215-17-9 (S)-2-((S)-2-((S)-2-Benzyloxycarbonylamino-5-{[1-phenyl-meth-(E)-ylidene]-amino}-pentanoylamino)-5-{[1-phenyl-meth-(E)-ylidene]-amino}-pentanoylamino)-5-{[1-phenyl-meth-(E)-ylidene]-amino}-pentanoic acid 

Relevant articles and documents

Practical synthesis of hydroxamate-derived siderophore components by an indirect oxidation method and syntheses of a DIG-siderophore conjugate and a biotin-siderophore conjugate

A practical large-scale synthesis of hydroxamate-derived siderophore components (30 and 40) that utilizes an efficient indirect oxidation method is described and applied to the syntheses of nonradioactive labeled siderophores. Oxidation of imines derived from L-ornithine (17) and its tripeptide (19) afforded oxaziridines that were isomerized to stable nitrones (16 and 18). Acid-catalyzed hydrolysis of nitrones provided hydroxylamines that were converted to the desired hydroxamic acids (30 and 40) suitable for constructing siderophore-drug conjugates (2). The entire synthetic sequence required no chromatographic separation. DIG- and biotin-labeled ferrichrome analogues designed to detect and isolate ferrichrome receptors in various microbes were also synthesized.